نتایج جستجو برای: spermatogonial transplantation
تعداد نتایج: 144019 فیلتر نتایج به سال:
Recent studies suggest a role for ERK1 in the regulation of spermatogonial proliferation. In this report the frog Rana esculenta, a seasonal breeder, was used as a model to study the possible effect on ERK1 of photoperiod and temperature. Adult male R. esculenta were subjected to several combinations of light and temperature at different times of the year to elucidate the regulation of ERK1 tes...
Abstract Background Spermatogonial stem cells (SSCs) in the testis are crucial for transferring genetic information to next generation. Successful transplantation of SSCs infertile men is an advanced therapeutic application reproductive biology research. Methods In this experimental research, both vitro and vivo characterization undifferentiated differentiated were performed by morphology—immun...
Mice that are ets variant gene 5 (ETV5) null (Etv5(-/-)) undergo the first wave of spermatogenesis but lose all spermatogonial stem cells (SSCs) during this time. The SSC loss in Etv5(-/-) mice begins during the neonatal period, suggesting a role for ETV5 in SSC self-renewal during this period. Herein, we show that Etv5 mRNA was present in perinatal mouse testis and that ETV5 was expressed in f...
OBJECTIVE Testicular cell transplantation has been widely used to investigate the restoration of fertility in rodent models. In this research we apply transplantation as a treatment method in the cryptorchid model and compare this method with orchidopexy, which is the routine treatment for this problem. We studied the controversial effects of treatment on the number of germ cells and other morp...
The complex process of spermatogenesis is regulated by various factors. Studies on spermatogonial stem cells (SCCs) have provided very important tool to improve herd genetic and different field. 0.2 to 0.3 percent of total cells of seminiferous tubules is consist of spermatogonial stem cells. To investigate and biomanipulation of these cells, proliferation and viability rate of cells should be ...
BACKGROUND Spermatogonial stem cells (SSCs), a subset of undifferentiated type A spermatogonia, are the foundation of complex process of spermatogenesis and could be propagated in vitro culture conditions for long time for germ cell transplantation and fertility preservation. OBJECTIVE The aim of this study was in vitro propagation of human spermatogonial stem cells (SSCs) and improvement of ...
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