Spinal cord compression caused by extramedullary hematopoiesis is a rare complication of chronic anemic states, most frequently occurring in patients with beta-thalassemia. We report the MR appearance of extramedullary hematopoiesis resulting in cord compression in a patient with a myelodysplastic syndrome, which was isointense with the spinal cord on T1-weighted images and markedly hypointense...

Spinal cord compression due to extramedullary hematopoiesis is a well-known complication in a number of hematological diseases. Most of the patients present with progressive paraparesis due to the slow expansion of the extramedullary hematopoietic tissue. The authors report a case of chronic myeloproliferative disorder with spinal extramedullary hematopoiesis presenting with acute paraplegia. C...

Extradural arachnoid cyst in the spine is an uncommon cause of spinal cord compression in the paediatric population. Most reported cysts have communication with the intrathecal subarachnoid space through a small defect in the dura. The reported child had spinal cord compression caused by a large spinal extradural arachnoid cyst in dorsal spine that did not communicate with the intradural subara...

According to recent Canadian statistics, an estimated 186,400 new cases of cancer and 75,700 deaths from cancer are expected in Canada in 20121. In general, between 40% and 70% of patients with advanced solid tumours such as those of breast, prostate, and lung will develop bone metastases2. The spine is the most common site for bone metastasis, affecting up to 30% of cancer patients3. Overall, ...

BACKGROUND AND PURPOSE Acute markers of spinal cord injury are essential for both diagnostic and prognostic purposes. The goal of this study was to assess the relationship between early MR imaging biomarkers after acute cervical spinal cord injury and to evaluate their predictive validity of neurologic impairment. MATERIALS AND METHODS We performed a retrospective cohort study of 95 patients ...

Metastatic Epidural Spinal Cord Compression The axial skeleton is a commonly involved site in patients with bone metastases. Progressive spinal metastasis may result in epidural spinal cord compression, and lead to paresis and paralysis if left untreated [1-3]. The treatment of metastatic epidural spinal cord compression is determined by disease factors such as histology, site of disease, exten...

BACKGROUND Cervical compressive myelopathy, e.g. due to spondylosis or ossification of the posterior longitudinal ligament is a common cause of spinal cord dysfunction. Although human pathological studies have reported neuronal loss and demyelination in the chronically compressed spinal cord, little is known about the mechanisms involved. In particular, the neuroinflammatory processes that are ...

The incidence of spinal cord injury (SCI) in the US is approximately 12,000 individuals annually, due to various forms of trauma and disease. (1) Previous studies show that increased force on or prolonged compression of the spinal cord results in progressive ischemia, as indicated by a reduction in spinal cord perfusion (3). Diminished flow over a prolonged period of time can cause necrosis and...

STUDY DESIGN  Case report. CLINICAL QUESTION  To report successful surgical therapy for spinal cord compression in a patient with spinal metastases from a pancreatic gastrinoma. METHODS  A 43-year-old man presented three times within 4 years with cervical and upper thoracic spinal cord compression because of metastatic gastrinoma. He had two previous spine metastases to the lower thoracic a...

complications are rare. Major textbooks and specialised books on osteoporosis either do not mention spinal cord compression as a complication of senile osteoporosis'-3 or state that it is rare or does not occur." Thus one book states, "Nerve root compression is rare and spinal cord damage does not occur even in the presence ofsevere deformity"5; another that, "Spinal cord compression does not o...