inflammatory myofibroblastic tumor (imt) in the spine or paraspinal area is extremely rare. here, we report a rare case of a 56-year-old man who had pathological-proven spinal epidural imt showing a malignancy-like infiltrative feature on mr imaging with alteration of t2 signal intensity on follow-up from slightly high to low compared with initial mr imaging. to the best of our knowledge, this ...

background: spine of an adult is made up of five areas that include 7 cervical vertebrae, 12 thoracic vertebrae, 5 lumbar vertebrae, sacrum and finally coccyx. selecting appropriate assumptions for modeling and biological analysis of the spine components has a significant impact on the accuracy of results in biomechanical simulation for different modes. methods: in the present study, biomechani...

Method The first concept is the mathematical model of circled helicoid. In the torso column, the generating circle is perpendicular to the axis. To obtain a torso column in the opposite side of scoliosis, the superposition of three electronic instantaneous full 3D moldings are necessary: First molding in self active axial elongation for pelvis and shoulders Second molding in lumbar shift and ph...

An outstanding question in research of central pattern generators is whether CPGs can be used for whole body control of a robot. Given the spine’s important role in walking, including a robotic spine may be a prerequisite for answering this question, but most current robots use rigid torsos. Tensegrity offers exciting possibilities for future robotic structures, as their continuous tension netw...

Dendritic spine morphogenesis contributes to brain function, cognition, and behavior, and is altered in psychiatric disorders. Kalirin is a brain-specific guanine-nucleotide exchange factor (GEF) for Rac-like GTPases and is a key regulator of spine morphogenesis. Here, we show that KALRN-knockout mice have specific reductions in cortical, but not hippocampal, Rac1 signaling and spine density, a...

Introduction Spinal muscles transmit most of the kinematical forces to the spine tissues and therefore, careful modelling of muscle activity is critical for an adequate estimation of spinal loads. However, current lumbar spine numerical models overlook such muscle contribution or suggest simplifications that do not allow thorough studies of load transfers within the deforming spine. As such, th...

to perform an accurate approach to the spine specially for fracture stabilization a 3d model of spine surgical region may improve this mechanism and it can help the surgeon to have a deeper glance to this scenario. the pre-op planning facility is another advantage of the patient spine specific model to take a chance of making guides to direct pedicle screws safely and increase the pathomechanic...

Mammalian Sterile 20 (Ste20)-like kinase 3 (MST3) is a ubiquitously expressed kinase capable of enhancing axon outgrowth. Whether and how MST3 kinase signaling might regulate development of dendritic filopodia and spine synapses is unknown. Through shRNA-mediated depletion of MST3 and kinase-dead MST3 expression in developing hippocampal cultures, we found that MST3 is necessary for proper filo...

Synaptic remodeling has been postulated as a mechanism underlying synaptic plasticity, and cadherin adhesion molecules are thought to be a regulator of such a process. We examined the effects of cadherin blockage on synaptogenesis in cultured hippocampal neurons. This blockade resulted in alterations of dendritic spine morphology, such as filopodia-like elongation of the spine and bifurcation o...