CONTEXT Tuberculosis is a common disease in the developing world and its incidence is slowly increasing in developed countries where a resurgence has been seen subsequent to the AIDS epidemic. Tuberculosis, in its extrapulmonary form, though emerging as a clinical problem, rarely affects the pancreas. The pancreas is biologically protected from being infected by Mycobacterium tuberculosis. Panc...

The heparin-binding hemagglutinin (HBHA) of Mycobacterium tuberculosis is a surface-expressed adhesin that can affect binding to host cells via a unique, methylated, carboxyl-terminal, lysine-, alanine-, and proline-rich repeat region. It has been implicated in extrapulmonary dissemination of M. tuberculosis from the lung following the initial infection of the host. To assess the vaccine potent...

case presentation a 27-year-old male, without a remarkable medical history, who suffered from abdominal pain for 2 days after falling was admitted to the emergency department with hypovolemic shock. upon performing emergency laparotomy a ruptured splenic artery aneurysm was found. conclusions it is important to consider rupture of a splenic artery aneurysm in patients with abdominal pain and hy...

BACKGROUND Fine-needle aspiration (FNA) of focal splenic lesions (FSL) is usually done under ultrasound (US) or computed tomography guidance. Endoscopic US (EUS), because of its ability to provide high-resolution images, can be used for aspirating FSL. We studied the safety and efficacy of EUS-guided FNA of FSL. METHODS We performed a retrospective analysis of patients with FSL undergoing EUS...

BACKGROUND/AIMS Hepatic or splenic lesions in hematologic patients are not defined well because they are not easy to evaluate due to limitations of invasive procedures. Management typically depends on the clinical diagnosis with few microbiological data. METHODS We reviewed the medical records of consecutive hematologic patients with hepatic or splenic lesions in the infectious diseases unit ...

splenic hamartoma is an unusual accidental finding with non-neoplastic feature that may be incidentally diagnosed because of its compression effect on surrounding organs. the predominant pathological feature leading diagnosis is circumscribed, un-encapsulated bulging nodules with focal fibrosis or cyst. the histopathological feature of splenic hamartoma is the positivity for cd8, and occasional...

Tuberculosis (TB) of the spleen is an extremely rare clinical entity particularly among immunocompetent persons. We report a case of isolated tuberculous abscess of spleen in a 13- years- old boy. No primary focus of infection was detected in lungs or any other organ. The patient was treated by splenectomy after a therapeutic failure with standard antituberculous medication.

primary splenic cyst is a rare entity and majority of the cases are classified as epithelial cysts. they are uncommon, comprising only about 10% of benign non-parasitic cysts. most of the cysts are asymptomatic, and they are incidental findings during abdominal ultrasonography. we report a case of 20 years old male who presented with 1 year history of mild abdominal pain and left upper quadrant...

The difficulty of treatment of kala-azar when associated with pulmonary tuberculosis has been recognized by all workers who have come across such cases. Napier (1937) considered pulmonary tuberculosis and kala-azar to be a fatal combination. He had observed that when kalaazar and pulmonary tuberculosis co-existed, antimony treatment had little or no effect on the symptoms, fever and splenic enl...