Otitis media is a common reason for hearing loss, especially in children. Otitis media is a multifactorial disease and environmental factors, anatomic dysmorphology and genetic predisposition can all contribute to its pathogenesis. However, the reasons for the variable susceptibility to otitis media are elusive. MCPH1 mutations cause primary microcephaly in humans. So far, no hearing impairment...

Inflammation of the middle ear, known clinically as chronic otitis media, presents in different forms, such as chronic otitis media with effusion (COME; glue ear) and chronic suppurative otitis media (CSOM). These are highly prevalent diseases, especially in childhood, and lead to significant morbidity worldwide. However, much remains unclear about this disease, including its aetiology, initiat...

BACKGROUND Otitis media is a more frequent occurrence in children, and the disease may progress from an acute to chronic state if appropriate and timely intervention is not initiated. METHODS A total of 212 children aged 6 months to 10 years were examined and treated for otitis media, in a 13-month hospital-based study. RESULTS Acute otitis media was diagnosed in 130 (61.3 per cent) of the ...

To assess the relation between early acute otitis media and exposure to respiratory pathogens mediated by siblings and other children, a prospective cohort of 3754 Norwegian children born in 1992-3 was followed up from birth to 12 months. Of these, 25% had one or more episodes of acute otitis media during the first year. Results from multiple logistic regression analysis adjusted for confoundin...

Serios otitis media is one of those ear Trou­bles that has enjoyed a very extensive research two decaides.  I ts recognition in medical literature goes b,ick tc eighteenth century. Since then there has been rather little progress in this field. The dis­covery of antibiotcs and thence lessening of in­ fecticus ear diseases, attention has been paid to preserve the function of ear, and naturally...

AIM To determine the possible correlation between otitis media and dental malocclusion in children. METHODS Fifty subjects (26 males and 24 females; mean age: 7.8 +/- 1 years) were assessed: 25 patients, with otitis media formed the study group, while 25 healthy subjects formed the control group. An otolaryngological examination and dental cast measurements were performed in order to evaluate...

BACKGROUND Previously rare A2ML1 variants were identified to confer otitis media susceptibility in an indigenous Filipino community and in otitis-prone US children. The goal of this study is to describe differences in the middle ear microbiome between carriers and non-carriers of an A2ML1 duplication variant that increases risk for chronic otitis media among indigenous Filipinos with poor healt...

BACKGROUND Recurrent otitis media is a common problem in young children. Echinacea and osteopathic manipulative treatment have been proposed as preventive measures, but have been inadequately studied. This study was designed to assess the efficacy of Echinacea purpurea and/or osteopathic manipulative treatment (OMT) for prevention of acute otitis media in otitis-prone children. METHODS A rand...

Bacteria Isolated from Otitis Media with Effusion in Children, Shiraz, Iran. Iran J Med Sci 2011;36 (4):273–80. 49. Šprem N, Pegan B, Glunčić I. Otologija. Bumber Ž, Katić V, Nikšić-Ivančić M i sur. Otorinolaringologija. Zagreb: Naklada Ljevak; 2004, str. 32–47. 50. Šprem N. Otologija. Krajina Z i sur. Dječja otorinolaringologija. Zagreb: Školska knjiga; 1998, str. 122–158. 51. Y Woo-Lee, Y Chu...

This reference guide contains highlights from the Clinical Practice Guideline, Otitis Media with Effusion in Young Children. The Otitis Media Guideline Panel, a private-sector panel of health care providers, developed the Guideline after comprehensively analyzing the research literature and current scientific knowledge of the development, diagnosis, and treatment of otitis media with effusion i...