نتایج جستجو برای: static strain aging

تعداد نتایج: 425742  

Journal: :Translational medicine @ UniSa 2015
Gaetano Santulli Consuelo Borras Jean Bousquet Laura Calzà Antonio Cano Maddalena Illario Claudio Franceschi Giuseppe Liotta Marcello Maggio William D Molloy Nunzia Montuori Rónán O'Caoimh Francesc Orfila Amelia P Rauter Aurelia Santoro Guido Iaccarino

Preclinical studies are essentially based on animal models of a particular disease. The primary purpose of preclinical efficacy studies is to support generalization of treatment-effect relationships to human subjects. Researchers aim to demonstrate a causal relationship between an investigational agent and a disease-related phenotype in such models. Numerous factors can muddle reliable inferenc...

Journal: :American journal of epidemiology 2014
Kristin Litzelman Whitney P Witt Ronald E Gangnon F Javier Nieto Corinne D Engelman Marsha R Mailick Halcyon G Skinner

The pathophysiological consequences of caregiving have not been fully elucidated. We evaluated how caregiving, stress, and caregiver strain were associated with shorter relative telomere length (RTL), a marker of cellular aging. Caregivers (n = 240) and some noncaregivers (n = 98) in the 2008-2010 Survey of the Health of Wisconsin, comprising a representative sample of Wisconsin adults aged 21-...

2015
Zhijian Zhou Jian Cui Xiaobing Ren

A strain glass state was found to be located between B2-B19' (cubic to monoclinic) phase transition and B2-R (cubic to rhombohedral) phase transition in Ti49Ni51 alloys after aging process. After a short time aging, strong strain glass transition was observed, because the size of the precipitates is small, which means the strain field induced by the precipitates is isotropic and point-defect-li...

Journal: :Construction and Building Materials 2021

• Quasi-static strain rate effect was experimentally investigated for modern rebars. Tensile strength increased up to 8% in the range of quasi-static rates. A simple model allows predict stress increase based on given Strain limits comparability mechanical properties quality control. can influence results structural tests with corroded While it has been known decades that even loading, incremen...

Journal: :Continuum Mechanics and Thermodynamics 2022

This article presents a series of experimental investigations on the viscoelastic behavior silica-filled and silver-filled silicone rubber unaged aged states. The study specific aging conditions relative to electronics industry is proposed in this work, namely hermetic, initially inert atmosphere, at high temperatures. Viscoelastic properties materials are measured through DMA tests. Strain swe...

2016
Sohair M. Khojah Anthony P. Payne Dagmara McGuinness Paul G. Shiels

There is a paucity of information on the molecular biology of aging processes in the brain. We have used biomarkers of aging (SA β-Gal, p16Ink4a, Sirt5, Sirt6, and Sirt7) to demonstrate the presence of an accelerated aging phenotype across different brain regions in the AS/AGU rat, a spontaneous Parkinsonian mutant of PKCγ derived from a parental AS strain. P16INK4a expression was significantly...

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