the asiatic hybrid lily, a bulbous ornamental plant, has a special position in the horticulture as cut flower. to overcome some problems in nutrition of bulb flowers, the use of hydroponic system and nutrient solution is important in the cultivation of these flowers. the asiatic hybrid lilium bulbs “tresor” cultivar, used for the current research were planted under 3 different calcium levels in...

We previously reported a synthetic Laponite® crosslinked pNIPAM-co-DMAc (L-pNIPAM-co-DMAc) hydrogel which promotes differentiation of mesenchymal stem cells (MSCs) to nucleus pulposus (NP) cells without additional growth factors. The clinical success of this hydrogel is dependent on: integration with surrounding tissue; the capacity to restore mechanical function; as well as supporting the viab...

Adult neural stem cells reside in a specialized niche in the subventricular zone (SVZ). Throughout life they give rise to adult-born neurons in the olfactory bulb (OB), thus contributing to neural plasticity and pattern discrimination. Here, we show that the neurovascular protein EGFL7 is secreted by endothelial cells and neural stem cells (NSCs) of the SVZ to shape the vascular stem-cell niche...

Introduction Cell intervention with autologous disc chondrocyte transplantation (ADCT) has been shown to enhance clinical recovery following discectomy (Quebec Pain disability assessment, Oswestry, and VAS)[1]. Limitations, such as expansion of autologous cells, have guided efforts to develop a process using adipose tissuederived stem and regenerative cells (ADRCs) harvested during surgical exp...

Degeneration of the intervertebral disc (IVD) is a major spinal disorder that causes back pain. Nucleus pulposus (NP) in the central of IVD dehydrates and become more fibrous in the IVD degeneration. NP cells undergo apoptosis with the degeneration of extracellular matrix (ECM) components. To replenish the NP cells and core ECM, bone marrow mesenchymal stromal cells (BMSCs) have been highlighte...

General Abstract Current treatments for the degenerated intervertebral disc (IVD) comprise pain management and invasive surgical interventions; both of them are aimed at relieving the pain instead of repairing the tissue and restoring the biological function of the disc. Cell-based tissue engineering may meet the clinical need for the repair or regeneration of a damaged tissue, and it might be ...

Over the past decade, it has become clear that neural stem cells in the adult mammalian brain continuously generate new neurons, predominantly in the hippocampus and olfactory bulb. However, the central issue of whether these new neurons participate in functional synaptic circuitry has yet to be resolved. Here, we use virus-based transsynaptic neuronal tracing and c-Fos mapping of odor-induced ...

Currently, degenerative disk disease (DDD) and the subsequent chronic lower back pain that results from it represent a significant source of morbidity and mortality worldwide. The available treatment modalities such as pain therapy and surgical interventions aim to provide symptomatic relief; however, they do not address the underlying pathophysiology of DDD. The disease also has high societal ...

OBJECTIVE To determine whether bacterial colonization of drains can be reduced by local antiseptic interventions. BACKGROUND Drains are a potential source of bacterial entry into surgical wounds and may contribute to surgical site infection after breast surgery. METHODS After institutional review board approval, patients undergoing total mastectomy and/or axillary lymph node dissection were...