BACKGROUND The main indication for carotid endarterectomy (CEA) is severity of carotid artery stenosis, even though most strokes in carotid disease are embolic. The relationship between carotid plaque volume (CPV) and symptoms of cerebral ischaemia, and the measurement of CPV by minimally invasive tomographic ultrasound imaging, were investigated. METHODS The volume of the endarterectomy spec...

BACKGROUND Our understanding of human coronary physiological behaviour is derived from animal models. We sought to describe physiological behaviour across a large collection of invasive pressure and flow velocity measurements, to provide a better understanding of the relationships between these physiological parameters and to evaluate the rationale for resting stenosis assessment. METHODS AND...

Backgrnd The physiological assessment of angiographically intermediate-severity stenoses remains problematic. Functional measurements of poststenotic intracoronary Doppler coronary flow reserve can be performed in humans but have not been correlated with hyperemic myocardial perfusion imaging or angiographic data in this patient population. Method and Resus Thirty-three patients undergoing diag...

Backgrnd The physiological assessment of angiographically intermediate-severity stenoses remains problematic. Functional measurements of poststenotic intracoronary Doppler coronary flow reserve can be performed in humans but have not been correlated with hyperemic myocardial perfusion imaging or angiographic data in this patient population. Method and Resus Thirty-three patients undergoing diag...

introduction: acquired tracheal stenosis can be created by various malignant or benign causes. the most common cause of acquired non-malignant tracheal stenosis is endotracheal intubation, even for a short period. argon plasma coagulation is a non-contact method of thermal hemostasis. argon plasma coagulation can be used easily and fast and has low depth of penetration.  methods: this study is ...

It has been reported that 30-40% of patients with aortic stenosis are hypertensive. In such patients, the left ventricle faces a double (i.e. valvular and vascular) pressure overload, which results in subsequent wall volume hypertrophy. From a clinical standpoint, it is difficult to separate the respective contributions of aortic stenosis and systemic hypertension to left ventricular burden and...

Objective Biochemical indicators such as N-terminal pro-brain type natriuretic peptide (NT pro-BNP) and high-sensitivity Creactive protein (hsCRP) predict mortality in acute coronary syndrome (ACS). However, little is known about the relationship of these factors with severity of coronary artery stenosis in patients with. Methods Three hundred and thirty-one subjects including 246 unstable angi...

Coronary atherectomy and coronary stenting effectively reduce the severity of coronary artery stenoses, but direct comparisons of these interventions with conventional balloon angioplasty have not been performed. To compare the immediate efficacy of these 3 interventions, the angiographic morphology and the severity of the residual coronary stenosis were quantitatively evaluated in 18 patients ...

Aortic stenosis is the most frequent valvular heart disease. In aortic stenosis, therapeutic decision essentially depends on symptomatic status, stenosis severity, and status of left ventricular systolic function. Surgical aortic valve replacement or transcatheter aortic valve implantation is the sole effective therapy in symptomatic patients with severe aortic stenosis, whereas the management ...

In the present study, the nonlinear model of non-Newtonian blood flow in cosine-shape stenosed elastic artery is numerically examined. The model is carried out for axisymmetric, two-dimensional and fully developed blood flow. The vessel wall is assumed to be have time-dependent radius that is important factor for study of blood flow. The cosine-shape stenosis convert to rigid artery by using a ...