CAN J ANESTH 54: 1 www.cja-jca.org January, 2007 8 Hernandez-Diaz S, Varas-Lorenzo C, Garcia Rodriguez LA. Non-steroidal antiinflammatory drugs and the risk of acute myocardial infarction. Basic Clin Pharmacol Toxicol 2006; 98: 266–74. 9 Kearney PM, Baigent C, Godwin J, Halls H, Emberson JR, Patrono C. Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory dru...

A case-control study was performed to determine whether aspirin confers a similar risk of bleeding from gastric or duodenal ulcers in the elderly as non-aspirin, non-steroidal anti-inflammatory drugs. The intake of analgesics in 230 patients with bleeding ulcers aged 60 and over and in hospital and community controls matched for age and sex was examined. Those who had taken aspirin were between...

The majority of patients who have undergone surgery experience moderate-to-severe postoperative pain. Asian tend to under-report pain and are consequently under-treated. Poor management increases the risk morbidity, prolonged opioid use, lower quality life outcomes chronic post-surgical Multimodal analgesia is cornerstone management. Non-steroidal anti-inflammatory drugs considered a core compo...

The objective of this chapter is to summarize the current standards of pain management in minor sports related musculoskeletal injuries. We also address the topical form of non-steroidal anti-inflammatory drug as an effective pain management option in an out-patient setting. Design: Quantitive systematic review of randomized controlled trials. Methods: The data was obtained through literature r...

Aspirin is generally regarded as a cause of gastric ulcer but the role of non-steroidal anti-inflammatory agents and paracetamol in the aetiology of peptic ulcer is unclear. To investigate this we conducted a case control study of 180 matched pairs of peptic ulcer patients and controls obtained from surgical and dermatology outpatient clinics. There were 95 gastric ulcer and 85 duodenal ulcer p...

Steroidal saponins are natural glycosidic compounds of amphiphilic character. Their diverse biological activities are directly related to the variability of their structural constitutive frameworks, aglycones, and sugars. Several studies have demonstrated the therapeutic potential of steroidal saponins by their capacity to induce program‐ med cell death in different tumor cell lines. The proces...

The objective of this chapter is to summarize the current standards of pain management in minor sports-related musculoskeletal injuries. This chapter also addresses the topical form of non-steroidal anti-inflammatory drug as an effective pain management option in an outpatient setting. Design: Quantitive systematic review of randomized controlled trials. Methods: The data was obtained through l...

background: peritendinous adhesions after repairing an injury to the digital flexor tendons are a major problem in hand surgery. non-steroidal anti-inflammatory drug therapy may affect tendon healing and the development of peritendinous adhesions. the aim of this study was to evaluate ibuprofen effect in patients function after flexor tendon surgical repair.   method: thirty-five patients, who ...

paris polyphylla smith var. yunnanensis, has been used in traditional chinese medicine for its antibiotic and anti-inflammatory properties; in addition it has been used to cure liver cancer in particular. in this current study, β-ecdysterone (1) and three pennogenin steroidal saponins (2-4) were isolated from the etoh extract of paris polyphylla var. yunnanensis, and then tested for their antit...

A range of androgen conjugates with non-conventional platinum(II) complexes have been synthesised with the aim of targeting tumour cells since many display elevated levels of the androgen receptor. The androgenic platinum conjugates are delivered into selected cells with improved efficiency (when compared to their non-steroidal analogues). The act of conjugating an androgen to a platinum(II) co...