Stevens-Johnson syndrome (SJS) is a hypersensitivity reaction that affects the skin and mucous membranes. In this case report patient had drug induced after taking treatment for bilateral leg edema, was hospitalized later diagnosed as SJS. Upon evaluation, increased serum creatinine, decreased albumin, urinary output almost an uric edema which are signs of acute kidney injury (AKI), common comp...

Erythema multiforme may be placed on a disease continuum that includes Stevens-Johnson syndrome and toxic epidermal necrolysis. It was first described in 1866 by Hebra as a skin disease with symmetrically distributed red papules, evolving within several days to form annular or iris-like shapes or blisters. The term multiforme described this evolution of primary lesions into different forms. In ...

Background Mycoplasma pneumoniae is widely known as the etiological agent of “atypical pneumonia”, the most common clinical aspects of the infection being bronchiolitis and acute tracheobronchitis. It can also determine extrapulmonary manifestation such as ear, nose and throat infections, neurological, cardiac or dermatological manifestations. Dermatological involvement is second most common, a...

QUESTION I recently diagnosed an erythema multiforme rash in several patients, two of whom had the major variant, Stevens-Johnson syndrome. Should these patients be managed with corticosteroids? ANSWER In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. T...

We report a case of bronchobronchiolitis obliterans associated with Stevens-Johnson syndrome diagnosed using bronchography and bronchoscopy in a 25-year-old man with dyspnea. Eighteen months prior to admission, the diagnosis of Stevens-Johnson syndrome due to anticonvulsant therapy was made at another hospital. On admission, the patient was wheezing and had overinflation of the lungs, with mark...

We treated a 53-year-old man with advanced squamous cell carcinoma of the lung who had developed Stevens-Johnson syndrome, a life-threatening cutaneous reaction, after systemic chemotherapy consisting of carboplatin and paclitaxel. A critical assessment disclosed circumstantial evidence pointing to paclitaxel as the likely cause of this complication. As far as we are aware, this account is the ...