Pigmented rabbits were given an intravitreous injection of 0.1 ml of various concentrations of test drug, and vitreous fluorophotometry was done 6 and 24 hr after injection. Dibutyryl cyclic adenosine monophosphate (AMP) and 8-bromo-cyclic AMP caused reversible intravitreous fluorescein leakage only at relatively high concentrations. Adrenergic agents that are effective stimulators of adenylate...

OBJECTIVE To study the psychometric qualities of a perceived self-efficacy in wheeled mobility scale. DESIGN Questionnaires. SUBJECTS Forty-seven wheelchair basketball players with spinal cord injury (elite n=25, recreational n=22, from 6 different countries). METHOD Based on the literature, and expert's and wheelchair user's comments, a new Self-Efficacy in Wheeled Mobility Scale (SEWM)1...

The new reforms of health systems in Latin American countries began in the 1990s as part of wider state reforms, promoted by the International Monetary Fund and World Bank. In Colombia, the new system called National Social Security System for Health (Sistema Nacional de Seguridad Social en Salud, SNSSS) was defined by the Law number 100, approved in 1993 by the Congress. Its regulation is unde...

Women of child-bearing age who are candidates for trial and possible implantation of a spinal cord stimulator (SCS) may express concerns regarding its effect on their ability to become pregnant, to maintain a pregnancy and to breastfeed. Despite the large number of SCS implanted worldwide there is a paucity of data regarding its effect on fertility and the course of the pregnancy. We describe a...

Bisphosphonates such as risedronate and ibandronate are widely used to treat a variety of bone resorption diseases, preventing protein prenylation and disrupting osteoclast function. Bisphosphonates also activate human gd T cells (expressing the Vg2Vd2 T cell receptor), and these activated gd T cells kill tumor cells. 3] There has thus been interest in using bisphosphonates in cancer immunother...

As so many students of bioelectrical phenomenona frequently remind us, it was Luigi Galvani who first reported his experiments in applying electrical currents to contract the muscles of frogs and sheep . Numerous attempts have since been undertaken to utilize that phenomenon for a variety of therapeutic purposes, many of them quite successful . One of the most notable is the heart pacemaker. El...

Highly enriched populations of B lymphoblasts have been isolated after culture with anti-Ig-Sepharose and compared with dendritic cells as stimulators of CD4+ T cells in the murine MLR. The two populations clearly differed in phenotype; anti-Ig blasts were FcR+, B220+, 33D1-, while dendritic cells were FcR-, B220-, 33D1+. However, as MLR stimulators, they shared many common features. Both cells...

For several years, researchers have developed techniques to replace and enhance the capabilities of our neural system by means of implantable electrical stimulation technologies. Even though important work has been done in this field, further progress must be accomplished in terms of miniaturization in order to ensure comfort, simpler surgical implantation procedures, and the capability of usin...

BACKGROUND Social media have been used to study many aspects of health and human behavior. Although social media present a unique opportunity to obtain unsolicited patient-reported outcomes, its use has been limited in plastic and reconstructive surgical procedures, including migraine nerve surgery. The goal of this study was to utilize the most popular social media site, Facebook, to evaluate ...