A neuroendocrine neoplasm (nen) is a tumor that originates in neuroendocrine cells capable of producing peptides or amines. neuroendocrine neoplasms of the digestive system are also referred to as gastroenteropancreatic neuroendocrine neoplasms (GeP nen) and constitute a heterogeneous group of growths originating from at least 15 types of specialized cells spread throughout the stomach, small i...

Gastric cancer is one of the most common neoplasms and an important cause of cancer-related death worldwide. Efforts to reduce its high mortality rates are currently focused on multidisciplinary management. However, surgery remains a cornerstone in the management of patients with resectable disease. There is still some controversy as to the extent of lymph node dissection for potentially curabl...

Adenocarcinoma is the most common histological type of gastric tumour, accounting for approximately 95% of all gastric carcinomas. Gastrointestinal stromal tumours (GISTs) are rare mesenchymal neoplasms of the digestive tract. Synchronous adenocarcinoma and gastrointestinal stromal tumour (GIST) occurring in the stomach is rare and very few cases have been reported in literature. Synchronous tu...

Gastric Neuroendocrine Tumors (NETs), formerly known as Gastric Carcinoids (GCs), are neoplasms derived from enterochromaffin cells of the stomach. This heterogeneous group of tumors has been historically divided into three types, best distinguished by etiology. Type I gastric carcinoids, comprising 70-80% of gastric neuroendocrine tumors, are associated with autoimmune chronic atrophic gastrit...

BACKGROUND Gastrointestinal stromal tumors (GISTs) represent 85% of all mesenchymal neoplasms that affect the gastrointestinal (GI) tract. These GISTs range in size from small lesions to large masses. Often they are clinically silent until they reach a significant size, so their discovery is usually incidental. CASE PRESENTATION A 67-year-old man was admitted at our general surgery department...

BACKGROUND Acinar cell carcinoma represents only 1-2% of exocrine pancreatic neoplasms. On exceptionally rare occasions, primary acinar cell carcinoma can occur in ectopic locations. Herein, we report a case of pure pancreatic-type acinar cell carcinoma arising in the stomach. CASE PRESENTATION A 54-year-old male presented with a gastric submucosal mass detected by endoscopic examination. Lap...

BACKGROUND Pancreatic neoplasms are usually characterized by ductal, acinar, or endocrine differentiation. Mixed exocrine and endocrine pancreatic tumours are extremely rare. Here, we report a case of pancreatic mixed acinar-endocrine carcinoma (MAEC) with multiple synchronous liver metastases that were treated with surgery and transcatheter arterial chemoembolization (TACE) that later recurred...

Malignant neoplasms (MNP) of the gastrointestinal tract in children are extremely rare and account for 1.2 % all MNP. According to world literature, incidence gastric cancer is no more than 0.05 cases MNP children. In national foreign only isolated stomach adolescents aged 10 18 years described. Clinical manifestations disease, as patients over age 18, non-specific – epigastric pain, loss appet...

spindle cell neoplasms are defined as neoplasms that consist of spindle-shaped cells in the histopathology. spindle cell neoplasms can affect the oral cavity. in the oral cavity, the origin of the spindle cell neoplasms may be traced to epithelial, mesenchymal and odontogenic components. this article aims to review the spindle cell neoplasms of the oral cavity with emphasis on histopathology.  ...

Extramedullary plasmacytomas are rare among plasma cell neoplasms and primary gastrointestinal plasmacytomas are even rarer and many of the cases are not detected until the disease advances. We reported a case of extramedullary plasmacytoma of stomach in a 46 yr old female who presented with complaints of dyspepsia and melaena. Upper gastrointestinal endoscopy revealed a nodule in the pylorus r...