Two cases of penetration of the left ventricular myocardium by benign peptic ulcer are reported. Twenty five similar cases in the world published work are reviewed. The condition is only possible when there are fibrous adhesions between the stomach and diaphragm and the pericardium. In addition, the left lobe of the liver may be small. Alternatively, an ulcer within a hiatus hernia may erode in...

Twenty freshly resected stomach specimens, each containing an ulcerated carcinoma, were studied in an attempt to determine the best site for gastric biopsy. Using endoscopic biopsy forceps multiple biopsies were obtained from various sites around the ulcer. Carcinoma was detected with similar frequency in biopsies from the slough and from the rim of the ulcer. The positive biopsy rate was incre...

n By strict definition, antrectomy refers to removal of the gastrin-secreting portion of the stomach and when combined with a vagotomy results in an 85% reduction in gastric acid secretion. In the 1960s and 1970s, antrectomy with or without vagotomy was routinely performed for treatment of benign gastric and duodenal ulcers but, due to pharmacologic developments in reducing acid secretion and e...

Glycyrrhiza glabra L. is used in folk medicine for treatment of stomach disorders including peptic ulcers. The hydroalcoholic extract of Glycyrrhiza glabra L. (HEGG) was evaluated for antiulcerogenic activity and acute toxicity profile in mice. Various doses of HEGG (50-200 mg/kg) were administered orally to animals of different groups. Omeprazole and cimetidine at doses of 30 and 100 mg/kg wer...