During spatial navigation, the head orientation of an animal is encoded internally by neural persistent activity in the head-direction (HD) system. In computational models, such a bell-shaped "hill of activity" is commonly assumed to be generated by recurrent excitation in a continuous attractor network. Recent experimental evidence, however, indicates that HD signal in rodents originates in a ...

OBJECTIVE To determine clinically related characteristics in patients with pure lower motor neuron (LMN) syndromes, not fulfilling accepted diagnostic criteria, who were likely to respond to intravenous immunoglobulin (IVIg) treatment. METHODS Demographic, clinical, laboratory and neurophysiological characteristics were prospectively collected from patients with undifferentiated isolated LMN ...

Motor neuron disease (MND) is a progressive neurodegenerative condition, affecting pyramidal neurons of the corticospinal tract (upper motor neurons (UMN)), brainstem motor nerve nuclei and spinal cord anterior horn cells (lower motor neurons (LMN)). Clinical presentation varies, according to the site(s) affected and the relative balance between UMN and LMN signs (see Table 1). The term ‘amyotr...

By employing the limit set dichotomy for essentially strongly order-preserving semiflows and the assumption that limit sets have infima and suprema in the state space, we prove a generic quasi-convergence principle implying the existence of an open and dense set of stable quasi-convergent points. We also apply this generic quasi-convergence principle to a model for biochemical feedback in prote...

In this paper, we first obtain a weak mean convergence theorem of Baillon’s type for generalized hybrid mappings in a Hilbert space. Further, using an idea of mean convergence, we prove a strong convergence theorem of Halpern’s type for generalized hybrid mappings in a Hilbert space.

The present essay scrutinizes the application of discrete mollification as a filtering procedure to solve a nonlinear backward inverse heat conduction problem in one dimensional space. These problems are seriously ill-posed. So, we combine discrete mollification and space marching method to address the ill-posedness of the proposed problem. Moreover, a proof of stability and<b...