BACKGROUND Intestinal strontium absorption is becoming accepted as a clinical and diagnostic tool for assessing intestinal calcium absorption in humans. However, little is known about whether intestinal strontium absorption, like that of calcium, is stimulated by calcitriol in healthy humans. METHODS The effect of calcitriol on intestinal strontium absorption was measured in eight healthy men...

This paper describes some physical, structural, and biological properties of gypsum bioceramics doped with various amounts of strontium ions (0.19-2.23 wt%) and compares these properties with those of a pure gypsum as control. Strontium-doped gypsum (gypsum:Sr) was obtained by mixing calcium sulfate hemihydrate powder and solutions of strontium nitrate followed by washing the specimens with dis...

Cortical granule exocytosis (CGE), also known as cortical reaction, is a calcium- regulated secretion that represents a membrane fusion process during meiotic cell division of oocytes. The molecular mechanism of membrane fusion during CGE is still poorly understood and is thought to be mediated by the SNARE pathway; nevertheless, it is unkown if SNAP (acronym for soluble NSF attachment protein)...

Biomineralisation offers the potential for in-situ sequestration and subsequent reduction in the bioavailability of heavy metals and radionuclides in the subsurface environment. Calcium carbonate minerals are known to sorb and form solid solutions with a range of target elements, and are readily produced by the actions of common microorganisms on simple chemical precursors. The ability of a com...

INTRODUCTION In osteoarthritis (OA) the progression of cartilage degeneration has been associated with remodeling of the subchondral bone. Human OA subchondral bone osteoblasts were shown to have an abnormal phenotype and altered metabolism leading to an abnormal resorptive process. Bone resorption is suggested to occur, at least in part, through the increased levels of two proteolytic enzymes,...

Through high-resolution electron microscopy, the surface structure of barium titanate and strontium titanate nanoparticles are found to be terminated by a TiO2 double layer. These results confirm prior observations of TiO2-rich surface reconstructions on strontium titanate nanoparticles made hydrothermally at high pH and single crystals prepared with wet chemical etching. Of all the reconstruct...

Both calcium and strontium could be transported actively from erythrocytes if adenosine triphosphate, guanosine triphosphate, or inosine triphosphate were included in the hypotonic medium used to infuse calcium or strontium into the cells. Acetyl phosphate and pyrophosphate were not energy sources for the transport of either ion. Neither calcium nor strontium transport was accompanied by magnes...

The calcium ion is required for the operation of a number of physiological processes, such as bone and tooth formation, blood coagulation, nerve impulse transmission, and muscle contraction. At the cellular-biochemical level, the calcium ion participates in signal transduction and is a significant factor in cell replication and cell division. The ultimate source of this important element is the...

Strontium ferrite nanoparticles were prepared by a coprecipitation method, and reduced graphene oxide/strontium ferrite/polyaniline (R-GO/SF/PANI) ternary nanocomposites were prepared by in situ polymerization method. The morphology, structure, and magnetic properties of the ternary nanocomposites were investigated by X-ray powder diffraction (XRD), Fourier transform infrared spectroscopy (FT-I...

Background: Previous preclinical findings reported that Strontium ranelate increases the secretion of osteoprotegerin (OPG) protein as well as mRNA levels and down-regulates both RANKL protein and mRNA expression in primary human osteoblasts; this increase in the OPG/RANKL ratio is known to negatively affect osteoclastogenesis. Objectives: The objective of the present study is to assess the eff...