X-ray crystallography is the most reliable method for structure elucidation and absolute configuration determination of organic molecules based on their single crystal forms. However, many analytes are hard to crystallize...

lycium species is a popular medicinal plant in the traditional chinese medicine and lycium ruthenicum is a native medicinal plant of iran. lycium genus has several biologically important properties too. investigation of chemical composition of ethyl acetate extract of this plant is the goal of this study. two coumarins (scopoletin and sculetin) and methyl-2-hydroxy-4-undecanoxy-trans-cinamate w...

The rootes of Chinese sage, Salvia miltiorrhiza Bunge (labieteae) are used to prepare an important traditional medicine in the Chinese pharmacoepia, Dan Shen. Indeed, related members of this genus are common traditional medicines throughout the world, making Salvia species the targets of intense phytochemical investigations. The active constituents of these species have been reported to be seve...

Background: Echinophora platyloba DC (Apiaceae) is one of the two endemic species of Echinophora genus in Iran. It has many folkloric uses and several biological activities but there is no information about its phytoconstituents. Objective: In this work some of the secondary metabolites were isolated, purified and identified from n-hexane, ethyl acetate and methanol extracts from the aerial pa...

H and C NMR spectra remain the first tool used by chemists to perform the structure elucidation of their products on a routine basis. It is common to provide NMR data on both proton and carbon spectra based on one-dimensional experiments. The increasing complexicity of natural compounds and their synthetic related derivatives implies the use of some more recent 1D and 2D NMR techniques. The pur...

background: echinophora platyloba dc (apiaceae) is one of the two endemic species of echinophora genus in iran. it has many folkloric uses and several biological activities but there is no information about its phytoconstituents. objective: in this work some of the secondary metabolites were isolated, purified and identified from n-hexane, ethyl acetate and methanol extracts from the aerial par...

Although significant advances have been made in recent years, the structural elucidation of small molecules continues to remain a challenging issue for metabolite profiling. Many metabolomic studies feature unknown compounds; sometimes even in the list of features identified as "statistically significant" in the study. Such metabolic "dark matter" means that much of the potential information co...

The nuclear Overhauser effect (NOE) is a powerful tool in molecular structure elucidation, combining the subtle chemical shift of NMR and three-dimensional information independent connectivity. Its usage for intermolecular studies, however, fundamentally limited by an unspecific long-ranged interaction behavior. This joint experimental computational work shows that proper selection interacting ...