Ayurvedic preparations claim on their label only the quantity of crude drugs and not the quantity of active ingredients present therein. So work was taken up to find the percentage of strychnine and brucine from Ayurvedic pills of Nux vomica powder by TLC spectrophotometric analysis, which study has not been reported earlier. However, the literature survey only revealed the following work.

OBJECTIVE The objective of the current study was to investigate the lateral dominance for a bimanually coordinated natural feeding behavior in semi-wild chimpanzees. METHODS Strychnos spp. fruit consumption behaviors in semi-wild chimpanzees as an ecologically comparable feeding behavior to those found in cerebral lateralization studies of non-primate species was investigated. Video recording...

The selective modulation of ATP-binding cassette (ABC) efflux pumps overexpressed in multidrug resistant cancers (MDR) and attendant resensitization to chemotherapeutic agents represent a promising strategy for treating cancer. We have synthesized four novel pentacyclic Strychnos alkaloids alstolucines B (2), F (3), and A (5) and N-demethylalstogucine (4), in addition to known Strychnos alkaloi...

Strychnos potatorum Linn.F. is a medicinally important endangered forest tree species which belongs to Loganiaceae and is also known as nirmali and clearing nut tree. In traditional medicinal systems like Ayurveda, Siddha and Greek, the plant parts are used for treating eye and urinary tract infections; gonorrhoea and kidney troubles, leucorrhoea, tuberculosis, diabetes, venereal diseases and a...

In 1897, Eduard Tangl observed striations between cells in the cotyledons of Strychnos nuxvomica and hypothesized that the “the protoplasmic bodies. . . are united by thin strands passing through connecting ducts in the walls, which put the cells into connection with each other and so unite them to an entity of higher order” (for review, see 2). This was a prophetic view of the symplasm, a term...

Isostrychnopentamine (ISP) is an indolomonoterpenic alkaloid that is present in the leaves of Strychnos usambarensis, a well known African shrub or little tree. The roots contain quaternary alkaloids, which are used to make a curare-like arrow poison. However, tertiary alkaloids isolated from the same plant possess cytotoxic activities against mammalian cells and protozoa. The effect of ISP has...

ETHNOPHARMACOLOGICAL RELEVANCE Traditional medicines play an important role in the management of chronically painful and debilitating joint conditions, particularly in the rural Africa. However, their potential use as sources of medicines has not been fully exploited. The present study was carried to find the medicinal plants traditionally used to manage chronic joint pains in Machakos and Maku...