OBJECTIVE To determine whether hepatic biochemical changes, as measured by routinely available tests indicative of hepatocellular necrosis, cholestasis, or altered hepatic clearance of bilirubin, occur in association with low to moderate exposure to styrene commonly experienced in industrial production. METHODS Two independent cross sectional studies were performed comparing serum hepatic tra...

polymer application for the improvement and modification of the bitumen used in roads surfaces has expanded in recent decades. the roads engineers and constructors, therefore, have used the modified bitumen in asphalts helping in this way to increase roads and pavements service life and improving the durability of the roads and asphalts. the bitumen used in asphalt mixture constitutes only a lo...

the increasing use of styrene, for the production of thermoplastics and rubbers, has given a special importance to this vital materialin petrochemical industries. more than 95 per cent of styrene production in the world is by dehydrogenation of ethylbenzene. present styrene production units are basically designed on the basis of 1940s units. producing countries and related research centres have...

attempts have been made for the first time to produce a friction material with thermal sensitive modulus by the inclusion of combined plastic/rubber properties of thermoplastic elastomers (tpe) as viscoelastic polymeric materials into the formulation for the purpose of increasing the damping behavior. in order to evaluate the viscoelastic parameters such as loss factor (tan δ) and elastic modul...

In this study, the adsorption mechanism and hydroxyl radical ((•)OH)-initiated photocatalytic degradation mechanism of styrene onto different (TiO2)n clusters were investigated using density functional theory. Styrene, a typical model atmospheric volatile organic compound (VOC), was found to be readily adsorbed onto (TiO2)n clusters through its vinyl group with strong chemisorption. This sugges...

Hemoglobin and albumin adducts of the carcinogen styrene-7,8-oxide (SO) were measured in 48 workers exposed to both styrene and SO in a boat manufacturing plant. Personal exposures to both substances were measured repeatedly over the course of 1 year (styrene:0.9-235 mg/m3 with a mean of 64.3 mg/m3 for 48 subjects; S0: 13.4-525 mu g/m3 with a mean of 159 mu g/m3 for 20 subjects). Cysteine and c...

Mice are particularly sensitive to respiratory tract toxicity following styrene exposure. Inhalation of styrene by mice results in cytotoxicity in terminal bronchioles, followed by increased incidence of bronchioloalveolar tumors, as well as degeneration and atrophy of nasal olfactory epithelium. In rats, no effects on terminal bronchioles are seen, but effects in the nasal olfactory epithelium...

with respect to the physical and mechanical limited qualities of bitumen, it benefits from certain specificability in application and its life service. polymers as the most important modifiers of bitumen are applied to it in order to improve its functional efficiency. among various polymers, styrene-butadiene- styrene (sbs) is the best modifier of the bitumen. in this work, sbs polymer as one o...

AIMS To investigate the relation between colour vision loss and the exposure level of styrene. Exposure level included the current exposure concentration, past cumulative exposure, and the maximum exposure level in the past. METHODS Colour vision was examined by the Lanthony desaturated panel D-15 test for 76 subjects exposed to styrene in a fibreglass reinforced plastics boat plant (as an ex...

We studied the relationship between DNA damage, DNA repair rates and messenger RNA (mRNA) expression levels of cell cycle genes TP53, p21(CDKN1A), BCL2 and BAX in a group of 71 styrene-exposed workers and 51 control individuals. The exposure was assessed by measuring the concentration of styrene at workplace and in blood. Parameters of DNA damage [measured as single-strand breaks (SSBs) and end...