Antibiotic-resistant enterococci are being increasingly identified as causal agents of infection. Trovafloxacin is a new fluoronaphthyridone with enhanced activity against gram-positive cocci and variable activity reported against Enterococcus spp. Twenty-one strains of vancomycin-resistant Enterococcus faecium and two strains of Enterococcus faecalis (one vancomycin resistant) were studied at ...

Objectives: Pseudomonas and Acinetobacter spp. which are usually resistant to many antibiotics, are the most important infectious pathogens in intensive care units (ICUs). The aim of this study was to determine the antibiotic resistance patterns of these agents and to follow variation in resistance among the years of 1999, 2006 and 2009. Methods: The resistance rates of various antibiotics for ...

OBJECTIVE Ampicillin plus sulbactam, an irreversible beta-lactamase inhibitor, was compared to cefoxitin in the treatment of women with acute pelvic inflammatory disease (PID) with and without inflammatory mass(es). METHODS Participation in an open, prospective, randomized clinical trial was offered to all women given the clinical diagnosis of acute PID who required inpatient therapy. Neisser...

and Klebsiella pneumoniae ATCC 700603 were used as control strains. The results were interpreted as per the CLSI (formerly NCCLS) criteria, except for ceftriaxone/sulbactam. Because there are no published breakpoints for the latter combination, the susceptibility criterion used for this combination was .8 mm increase in zone diameter of ceftriaxone/sulbactam in comparison with that of ceftriaxo...

BACKGROUND Multidrug-resistant (MDR) Acinetobacter baumannii are increasingly encountered and frequently susceptible only to colistin with their MIC values close to resistance breakpoint. Antibacterial activity of two carbapenem-based combinations were explored in order to overcome the bacterial resistance. MATERIAL AND METHOD Thirty clinical isolates of MDRA. baumannii were employed to asses...

aim : the present study aimed to compare the eradication rate of h. pylori by traditional amoxicillin, metronidazole, bismuth, and omeprazole regimen, with a new one using clarithromycin, omeprazole and ampicillin/sulbactam (penbactam). background : due to the appearance of amoxicillin-resistant h. pylori strains all over the world, the decreased efficacy of conventional amoxicillin-containing ...

Introduction: The incidence of postneurosurgical Acinetobacter baumannii ventriculitis/meningitis, primarily due to drug-resistant strains, has increased considerably in recent years. However, limited therapeutic options are available because most antibiotics poorly penetrate the blood-brain barrier, especially pediatric patients. Case Presentation: A five-year-old boy developed ventriculitis e...