BACKGROUND The aim of this study was to compare the long-term efficacy of entecavir (ETV) and lamivudine (LAM) therapy in children with chronic hepatitis B (CHB) who had not received nucleoside analogue treatment. METHODS In this multicenter, retrospective study, we included pediatric CHB patients younger than 20 years who received ETV or LAM treatment for at least 12 months and had no concom...

Oral antiarrhythmic treatment with mexiletine and disopyramide was evaluated in 34 patients with recurrent sustained ventricular tachycardias by programmed ventricular stimulation, except in a few instances where spontaneous attacks occurred under therapy. Coronary heart disease was present in 17 patients, cardiomyopathy in 11, myocarditis in five, and mitral valve prolapse in one. Complete sup...

We studied the mechanism of post-overdrive suppression in superfused rabbit sinus node pacemaker cells. Small specimens of sinus node tissue isolated from rabbit hearts were driven at a fast rate (overdrive) for 10-120 seconds using single sucrose gap methods. During the control perfusion (35 degrees C Tyrode's solution), overdrive caused a progressive decrease in maximum diastolic potential (M...

Deoxyuridine suppression tests have been performed by two different methods of six normoblastic and eight megaloblastic marrows. A good correlation was obtained between the results by the modified and the original methods. The simplified method was found to be applicable for a clinical purpose to diagnose megaloblastosis in the marrow. Uptake of 3H-deoxyuridine into DNA and effect of various co...

Unconditioned and conditioned effects of house-light offset and acoustic white noise on barpressing behavior maintained by intermittent food reinforcement were tested in male hooded rats. Presentations of these stimuli prior to their acquiring signal value initially tended to depress and then to enhance barpressing rate, but generally the rate of the on-going barpressing was lower during the li...

A generic model for advection of a scalar by E 3 B flow with a linearly varying mean shows that the cross phase factor in the transport flux is strongly reduced in the strong shear regime (shearing rate . eddy turnover rate), leading to significant transport suppression. The cross phase scales much more strongly with shear strength than do fluctuation amplitudes, allowing significant transport ...

objective: in recent years, there has been a rising interest in cognitive behavioral research to explore the role of emotion regulation in the development and maintenance of mental disorders and resiliency against or recovery from them. particularly, different strategies people use to regulate their emotions may have more important role in emotional disorders including depression. the aim of th...

Numerically determined ionization rates for the field ionization of atomic hydrogen in strong and short laser pulses are presented. The laser pulse intensity reaches the so-called “barrier suppression ionization” regime where field ionization occurs within a few half laser cycles. Comparison of our numerical results with analytical theories frequently used shows poor agreement. An empirical for...

We report on a series of measurements of decoherence and wave-packet dephasing between two colliding, strongly coupled, identical Bose-Einstein condensates. We measure, in the strong-excitation regime, a suppression of the mean-field shift, compared to the shift which is observed for a weak excitation. This suppression is explained by applying the Gross-Pitaevskii energy functional. By selectiv...

realizing the cause of cushing's syndrome (cs) is one of the most challenging processes in clinical endocrinology. the long high dose dexamethasone suppression test (standard test) is costly and need an extended inpatient stay. in this study we want to show the clinical utility of the overnight 8 mg dexamethasone suppression test (dst) for differential diagnosis of cs in a referral center. retr...