The SAD kinases are conserved regulators of neuronal polarity and synapse morphology. Although SAD kinases have been shown to play many different roles, the pathways through which they function remain largely unknown. Knockout mice for mammalian SAD kinases die immediately after birth. By contrast, C. elegans sad-1 genetic null mutants are healthy and viable, but exhibit a specific and fully pe...

Abstract : Video Compression (VC) is one of the resource hungry key element in video communication and is commonly achieved using Motion Estimation (ME). In this paper we proposed power efficient one bit full adder and one of the simple and easy metric called Sum of Absolute Difference (SAD) for estimating the motion vectors in motion estimation. SAD is primarily used to detect motion in the vi...

Extrinsic cues activate intrinsic signaling mechanisms to pattern neuronal shape and connectivity. We showed previously that three cytoplasmic Ser/Thr kinases, LKB1, SAD-A, and SAD-B, control early axon-dendrite polarization in forebrain neurons. Here, we assess their role in other neuronal types. We found that all three kinases are dispensable for axon formation outside of the cortex but that ...

Artworks with sad and affectively negative content have repeatedly been reported to elicit positive aesthetic appreciation. This topic has received much attention both in the history of poetics and aesthetics as well as in recent studies on sad films and sad music. However, poetry and aesthetic evaluations of joyful and sad poetry have received only little attention in empirical studies to date...

Systems analysis and design (SAD) is a core part of systems development and the Information Systems curriculum (Gorgone et al, 2002; Bajaj et al, 2004). SAD is a complex process, with many techniques used to understand problems and design solutions. This paper investigates how an agile software development approach may be used for the teaching and learning of SAD. The research reviews and compa...

Exaggerated anticipatory anxiety during expectation of performance-related situations is an important feature of the psychopathology of social anxiety disorder (SAD). The neural basis of anticipatory anxiety in SAD has not been investigated in controlled studies. The current study used functional magnetic resonance imaging (fMRI) to investigate the neural correlates during the anticipation of p...

Introduction: The study’s main aim is to investigate the long-term variation of Aerosol Optical Depth (AOD). It also aims to show the relationship between meteorological parameters. This study evaluates long-term (2010 to 2021) special and temporal changes over major Indian regions using satellite-based data from NASA’s Terra Satellite. Materials and Methods: This study was carried out during ...

Music emotion recognition and recommendation systems often use a simplified 4-quadrant model with categories such as Happy, Sad, Angry, and Calm. Previous research has shown that both listeners and automated systems often have difficulty distinguishing low-arousal categories such as Calm and Sad. This paper seeks to explore what makes the categories Calm and Sad so difficult to distinguish. We ...

BACKGROUND The sagittal abdominal diameter (SAD) measured in supine position is an alternative adiposity indicator that estimates the quantity of dysfunctional adipose tissue in the visceral depot. However, supine SAD's distribution and its association with health risk at the population level are unknown. Here we describe standardized measurements of SAD, provide the first, national estimates o...