Inhalation of drugs for both medicinal and recreational purposes has occurred for centuries. Over the last two decades, a variety of new formulation technologies and inhaler devices have been developed to repurpose drugs given by other routes of administration as superior inhalation products with improvements in safety, efficacy and convenience for patients. These efforts have been particularly...

Exanthematous reactions with various morphological and localization patterns are the most frequently encountered adverse drug reactions involving the skin. The time course of benign exanthemas typically encompasses a few days to some weeks. They are not complicated by severe systemic symptoms or internal organ involvement. They manifest themselves in a polymorphous manner with primary effloresc...

Division of Rheumatology, Allergy and Clinical Immunology, and Departments of Neurology, and Radiology, Chang Gung Memorial Hospital, Taoyuan. Received: 15 November 2001. Revised: 14 December 2001. Accepted: 2 April 2002. Reprint requests and correspondence to: Dr. Lieh-bang Liou, Division of Rheumatology, Allergy and Clinical Immunology, Chang Gung Memorial Hospital, 5 Fu-Hsing Street, Kwei Sh...

Both prescription drugs and illicit substances have been associated with the formation of aortic aneurysms, ruptures of aortic aneurysms, and acute aortic dissections. Most of the clinical information exists as single case reports and case series, but causal relationships have for many drug groups been substantiated on the basis of the known mechanisms of action of the drugs as well as from exp...

The article presents updated guidelines developed by the American College of Rheumatology and Association Hip Knee Surgeons on perioperative treatment patients with rheumatoid arthritis, ankylosing spondylitis, psoriatic juvenile idiopathic arthritis systemic lupus erythematosus undergoing elective total hip or knee arthroplasty. use anti-rheumatic drug therapy, including traditional disease-mo...

Rheumatoid arthritis is a chronic systemic inflammatory disease that affects approximately 0.5-1% of the world population. The current approach to this disease is to start an intensive treatment without delay once the disease has developed. Various studies in the literature have shown that combination of disease modifying antirheumatic drugs such as sulfasalazine and chloroquine offers a more a...

Dear Readers, Denture-induced stomatitis is the most common type of oral candidosis and the most frequent mucosal alteration associated with complete or removable partial dentures in the elderly. Despite being an infection of multifactorial etiology, this condition has as main etiological factor the colonization of denture-bearing mucosa and acrylic bases by species of Candida spp., especially ...