Shishido, Toshiaki, Masaru Sugimachi, Osamu Kawaguchi, Hiroshi Miyano, Toru Kawada, Wataru Matsuura, Yasuhiro Ikeda, and Kenji Sunagawa. Novel method to estimate ventricular contractility using intraventricular pulse wave velocity. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H2409–H2415, 1999.—We developed a novel technique for estimating ventricular contractility using intraventricular puls...

Changes in volume elasticity (VE) of the left ventricle and aorta could be important for blood flow. A procedure is presented to rapidly assess VE of the left ventricle and aorta by analyzing changes in the eigenfrequency. Six control rabbits and 11 rabbits with atheromatosis (12 wk of high-cholesterol feeding) were studied. In control rabbits, during the first half of the systole, left ventric...

• The influence of heniodynamic variables on the duration of certain phases of ventricular systole has been studied by several investigators in intact animals and in isolated heart preparations.' Even in isolated hearts, it is not possible to change one heniodynainic variable without inducing changes in one or more intrinsic determinants of the heart's performance. For example, augmenting strok...

RATIONALE AND OBJECTIVES Studies suggest that electrocardiographically gated coronary computed tomographic angiography provides a clear definition of the left ventricular outflow tract (LVOT), and normal LVOT morphology may not be round, as assumed when the continuity equation is applied during echocardiography. The aims of this study were to demonstrate the morphology of the LVOT on coronary c...

Relations between movement of the atrioventricular ring and changes in left atrial and ventricular dimensions were studied by echocardiography and compared with apexcardiography and Doppler mitral flow velocity traces in 20 healthy controls and in patients with left ventricular hypertrophy (n = 28) or dilatation (n = 16). During left ventricular systole the atrioventricular ring, a structure co...

Systole causes a redistribution of coronary blood flow away from the subendocardium. In the present study the relative contribution of shortening of the myocardial fibers (wall strains) and of pressure development in the ventricular lumen to redistribution were determined. The distribution of coronary blood flow during systole in hearts ejecting into a severed aorta (large wall strains and near...

This study was designed to quantify and compare transmural myocardial blood flow in the right and left ventricles of awake dogs during systole and diastole, and during total coronary artery occlusion. Studies were performed in six awake dogs chronically prepared with electromagnetic flowmeters and pneumatic occluders on the left circumflex and right coronary arteries. Intermittent coronary perf...

Introduction: Vasodilatory stress is the standard paradigm for probing myocardial oxygenation (O2) changes due to coronary artery stenosis on the basis of BOLD MRI (1-3). However, since vasodilation is typically achieved with provocative stress, approaches that can identify the presence of stenosis on the basis of microvascular alterations at rest are highly desirable. It is known that myocardi...

BACKGROUND Left ventricular aneurysm (LVA) is a significant complication of myocardial infarction that may lead to global left ventricular (LV) dysfunction. However, the exact mechanism underlying the abnormal function has not been elucidated. In this study we tested the hypothesis that changes in LV geometry cause both an increase in wall stress and a change in the temporal distribution of str...