BACKGROUND The aim of this randomized controlled study was to determine whether octreotide (OCT) or scopolamine butylbromide (SB) was the more effective antisecretive drug controlling gastrointestinal (GI) symptoms due to malignant bowel obstruction (MBO) caused by advanced ovarian cancer. METHODS Ninety-seven advanced ovarian cancer patients with inoperable MBO were randomized to OCT 0.3 mg/...

PURPOSE To determine the potential risk of contamination of a trypan blue bottle (TB) after first use and after being stored under different temperature and humidity conditions, as well as to identify possible contamination factors, most frequently involved microorganisms and simultaneously evaluate bacteriostatic and bactericide properties of the dye. METHODS An experimental and prospective ...

PURPOSE Prospective detection of patients with advanced rectal cancer (LARC) who have a higher probability of responding to preoperative chemoradiotherapy (CRT) may provide individualized therapy. Lipidomics is an emerging science dedicated to the characterization of lipid fingerprint involved in different pato-physiological conditions. The purpose of this study is to highlight a typical lipid ...

The theme of this paper is the extension of continuous valuations on the lattice of open sets of a T0-space to Borel measures. A general extension principle is derived that provides a unified approach to a variety of extension theorems including valuations that are directed suprema of simple valuations, continuous valuations on locally compact sober spaces, and regular valuations on coherent so...

BACKGROUND To evaluate the efficacy and safety of an intravitreal dexamethasone implant (Ozurdex®; Allergan Inc, Irvine, CA, USA) in patients with persistent diabetic macular edema (DME) over a 6-month follow-up period. METHODS Seventeen patients (20 eyes) affected by DME were selected. The mean age was 67 + 8 years, and the mean duration of DME was 46.3 + 18.6 months. The eligibility criteri...

INTRODUCTION Postoperative care after oesophageal tumour resection holds a high risk of respiratory complications. We therefore aimed to determine the value of systemic inflammatory markers in predicting arterial hypoxaemia as the earliest sign of developing lung injury after oesophageal tumour resection. METHODS In a prospective observational study, 33 consecutive patients were observed for ...

to investigate the xenoreactive immune response directed at Galα1, 3-Galβ1-4GlcNAc-R (α-Gal) which is known to be a major barrier in xenotransplantation, and to identify factors such as age, gender, ABO group and type of implanted tissue that might affect the anti-α-Gal immune response in adults subjected to bioprosthetic heart valve (BHV) implantation. Methods: A total of 103 early survivors a...

and Applied Analysis 3 delay. In the end, an example is provided to illustrate the effectiveness and the advantages of the results obtained. 2. Preliminaries Let R denote the set of real numbers, R the set of nonnegative real numbers, Z the set of positive integers, and R the n-dimensional real space equipped with the Euclidean norm | · |. Let τ > 0 and PC −τ, 0 ;R {φ : −τ, 0 → Rn|φ t φ t for a...

INTRODUCTION The study objectives were to analyze the presence of reduced bone mass in a sample of patients with anorexia nervosa (AN) and amenorrhea, to assess Bone Mineral Density (BMD) recovery after having a normal weight is reached and regular menses are resumed, and to predict BMD after a treatment period considering different variables (baseline BMD, baseline and final body mass index (B...

Aquaporin-2 (AQP-2), a water channel located on the apical membrane of collecting duct cells, regulates water reabsorption under the control of vasopressin (AVP). Using an antibody directed to human AQP-2, a quantitative Western blot analysis was performed to determine the collecting duct responsiveness to an oral, nonpeptide, V2 receptor antagonist (VPA-985) in patients with chronic NYHA II an...