A proportionate mortality study of miners and milers of talc containing asbestiform tremolite has shown an excess of lung cancer and one case of mesothelioma. Another cohort study ofworkers mining and milling talc containing tremolite, anthophyllite and serpentine mineraIs revealed significant excess mortality from lung cancer and from nonmalignant respiratory disease. Mortality from lung cance...

The effects of magnesium stearate, sodium lauryl sulphate (SLS) and talc as lubricants on some powder and tablet properties of silicified microcrystalline cellulose (SMCC) were studied. Single and binary blends of talc, magnesium stearate and SLS at 1% concentration were evaluated as flow modulators on SMCC. Influence of the lubricants on the powder and tablet properties of metronidazole was al...

STUDY OBJECTIVE To determine whether the administration of antiinflammatory drugs interferes with experimental pleurodesis induced by silver nitrate or talc. STUDY DESIGN Two groups of 30 white New Zealand rabbits were scheduled to receive an intrapleural injection of 0.5% silver nitrate or 400 mg/kg of talc. Each group was further classified into three subgroups (10 animals each), which rece...

The interaction between cleaved talc surfaces and hydrophobic probe particles, silanized silica and thiolized gold, has been investigated employing the atomic force microscopy (AFM) colloidal probe technique. These model systems have hydrophobicities similar to some of the talc-pitch c s a t T ©

Chemical pleurodesis is an effective treatment modality to reduce recurrence of malignant effusion. Several agents have been used in chemical pleurodesis but, it is not yet clear which is better. Eighteen Sprague-Dawley rats were used and classified into three groups: a group intrapleurally injected normal saline (group A, n=6), 400mg/kg talc (group B, n=6), and 9mg/kg mistletoe extraction (ME)...

OBJECTIVE The purpose of this study was to determine if a small pneumothorax would influence the pleurodesis resulting from talc instillation. METHODS Sixty rabbits received an intrapleural injection of 400 mg/kg talc slurry. One half also received 10 mL of air intrapleurally after the talc. Ten rabbits in each group were killed 2, 14, and 28 days after instillation. RESULTS Two days after ...

To analyze the correlation between asbestos lung burden and lung cancer, lungs of 211 female cases with and without lung cancer were examined. Phase-contrast microscopic (PCM) counting of ferruginous (FBs) and uncoated fibers (UFs), which had length longer than 5 microns and aspect ratios greater than 3:1, revealed a significantly higher level of FBs plus UFs in urban lung cancer cases than urb...

‘‘Stickies” are tacky spe tions, adhesives etc. Th deposit build-up. To su to the recycled stock. W mer adsorbing from col commercial preparation simple analogue to the i and cationic sites prese form to the Langmuir m two stage process invol tial aggregation. Talc pla appears to involve three molecules and the talc e surfaces, and finally by