Blood nicotine, cotinine, and carboxyhaemoglobin (COHb) concentrations were measured in 392 smokers (255 women and 137 men) of "middle tar" (17-22 mg), "low to middle" (11-16 mg), and "low tar" (less than 11 mg) cigarettes. Since tar intake cannot yet be measured directly, we devised an index to estimate it based on the use of measured levels of an intake marker (eg, blood nicotine) and the rat...

Tartrazine (Tar) is a yellow colorant widely used in food products, drugs and cosmetics. The current study evaluates the effect of ingestion of Tar at doses of 1%, 3% of diet on depression, anxiety and antisocial behavior then comparing between its effect and the combined effect of each dose with curcumin (Cur) (natural yellow color). Forced swimming test, open field test and social interaction...

The HIV-2 TAR RNA domain (TAR-2) plays a key role in the trans-activation of HIV-2 transcription as it is the target for the Tat-2 protein and several cell factors. Here, we show that the TAR-2 domain exists in vitro in two global, alternative forms: a new, extended hairpin form with two conformers and the already proposed branched hairpins form. This points strongly to the structural polymorph...

Co-pyrolysis of Shenmu coal (SM) and cotton stalk (CS) at different blend ratios were carried out in a tubular furnace. The pyrolysis temperature was up to 600 °C at 5 °C/min and kept for 15 min. The results indicated that there was an interactive effect between SM and CS, which increased the tar yield. Moreover, the content of light components in co-pyrolysis tar from all CS/SM blend ratios wa...

STUDY OBJECTIVE The aim was to determine if there was a relationship between cigarette tar yield and rates of chronic cough and chronic phlegm. SETTING 22 districts across Scotland were used for the Scottish Heart Health Study (SHHS) which was conducted between 1984 and 1986 and from which the data for this analysis were obtained. SUBJECTS 10,359 men and women aged 40-59 years were studied....

Numerous studies, mostly case reports, have found that occupational exposure to coal tars or coal-tar pitches (coal-tar distillates) is associated with skin cancer, including scrotal cancer; workers in these studies have included patent-fuel (coal-briquette) workers, pitch loaders, workers in electrical trades, and optical-lens polishers (IARC 1985, 1987). A 1946 study in the United Kingdom fou...

Fourteen cigarette brands manufactured in Nigeria in 1981 were analysed to determine the tar, nicotine, and carbon monoxide yields. Five of the brands belonged to the high and middle to high tar category (greater than 22 mg/cigarette) and nine to the middle tar (17-22 mg/cigarette) category. None of the cigarettes was in the low to middle and low tar (less than 17 mg/cigarette) category. The ni...

A major concern (or opportunity?): The price of oil was growing very rapidly, from $28 in 2003 to $38/barrel in 2005 and occasionally to above $80 in 2006 and peaking at $147 in 2008, but then precipitously dropping to $40 by the end of 2008. The peak price is 1–2 orders of magnitude higher than the cost of extraction, possibly meaning that financial speculation is overwhelming supply and deman...

The growing global demand for sustainable technologies that improves the efficiency of petrochemical processes in the oil industry has driven advances in petroleum biotechnology in recent years. Petroleum industry uses substantial amounts of petrochemical-based synthetic surfactants in its activities as mobilizing agents to increase the availability or recovery of hydrocarbons as well as many o...

tat, the trans-activator protein for human immunodeficiency virus 1 (HIV-1), has been expressed in Escherichia coli from synthetic genes. Purified tat binds specifically to HIV-1 trans-activation-responsive region (TAR) RNA in gel-retardation, filter-binding, and immunoprecipitation assays. tat does not bind detectably to antisense TAR RNA sequences, cellular mRNA sequences, variant TAR RNA seq...