: Esophageal cancer consists of two distinct histological types, esophageal squamous cell-carcinoma (ESCC) and adenocarcinoma (EAC). carcinoma is a grave malignancy with regards to prognosis mortality. ESCC remains the dominant type worldwide, about 90 percent all cases worldwide. However, EAC now much more common in United States Western World, represents one fastest growing cancers there. Des...