PURPOSE To clarify the effect of tradional Chinese medicine (TCM) on different stage patients and to explore medication duration based on survival analysis. RESULTS 523 and 294 patients were respectively in the TCM group and the control group. For all patients, 6-year disease-free survival (DFS) was 57.6% after TCM and 46.6% after non-TCM (p = 0.0006). 6-year DFS for patients with stage I dis...

BACKGROUND Heart failure (HF) is associated with decreased quality of life, high re-admission rate and poor prognosis. In particular, ischemic heart failure (IHF) has a worse prognosis than nonischemic HF. The use of traditional Chinese medicine (TCM) alongside Western medicine to treat HF has developed into an integrative treatment model in China. There have been small clinical trials and expe...

Objective To probe into the use of TCM preparations in the secondary prevention and treatment of CHD in China and investigate its influencing factors and relationship with guideline-recommended therapies. Methods A cross-sectional survey was conducted among 2,803 CHD outpatients, a representative sample of China. Interviewers (physicians) were assigned to collect information concerning patients...

Traditional Chinese medicine (TCM) has produced impressive responses in treatment of acquired immunodeficiency syndrome (AIDS) patients. However, various terms, such as principle, standard, assumption, convention, and concept, for TCM treatment are not accepted by conventional AIDS experts. The increasing popularity of TCM has also inspired horror about their toxicity and uncertainty of complex...

In the recent years, a wide range of metabonomic technologies are widely used in the modern research of traditional chinese medicine (TCM). At present, the most prevailing methods for TCM research are mainly nuclear magnetic resonance (NMR), gas chromatography-mass spectrometry (GC-MS), and liquid chromatography-mass spectrometry (LC-MS). With these techniques, metabonomics will help to underst...

Objective The aim of this review is to characterize current status of global TCM clinical trials registered in ClinicalTrials.gov. Methods We examined all the trials registered within ClinicalTrials.gov up to 25 September 2015, focusing on study interventions to identify TCM-related trials, and extracted 1,270 TCM trials from the data set. Results Overall, 691 (54.4%) trials were acupunctur...

Traditional Chinese Medicine (TCM) developed based on ancient Chinese philosophy. Its characteristics include abstract theories, fuzzy concepts, subjective diagnostic methods and it lacks clarity, and rigor as well as vindication from modern sciences, which makes development of TCM remain stagnant. Thus, how to free the theory of TCM from heavy philosophy to achieve separation of medicine and p...

Adoptive cellular immunotherapy using in vitro expanded CD8+ T cells shows promise for tumour immunotherapy but is limited by eventual loss of function of the transferred T cells through factors that likely include inactivation by tolerogenic dendritic cells (DC). The co-inhibitory receptor programmed death-1 (PD-1), in addition to controlling T-cell responsiveness at effector sites in malignan...

Traditional Chinese medicine (TCM) is currently the best-preserved and most influential traditional medical system with the largest number of users worldwide. In recent years, the trend of TCM adoption has increased greatly, but the process of TCM internationalization has suffered from a series of setbacks for both internal and external reasons. Thus, the process of TCM internationalization fac...

OBJECTIVES The increasing use of complementary, alternative medicine (CAM) and traditional Chinese medicine (TCM) has attracted attention. We report on the gender difference in TCM use among the general population in Taiwan in a population-based, cross-sectional study. METHODS We collected data on socio-demographic factors, lifestyle and health behavior from the 2001 Taiwan National Health In...