BACKGROUND There is no standard management of chronic hepatitis B (CHB) patients with suboptimal response to nucleoside/nucleotide analogues (NAs). This study aimed to evaluate two different NA combination therapies in patients with suboptimal response to adefovir (ADV). METHODS In this study, 72 CHB patients with suboptimal response to ADV were assessed, with 37 patients receiving lamivudine...

INTRODUCTION To assess the outcomes of immediate LDT versus observation strategies for T1 hepatocellular carcinoma (HCC) with respect to progression beyond Milan and survival. METHOD T1 HCCs were retrospectively reviewed from a multidisciplinary tumour board database between September 2007 and May 2015. In the observation group, T1 lesions were observed until the tumour grew to meet T2 criter...

The current study explores a set of variables that have the potential to predict semantic priming effects for 300 prime-target associates at the item level. Young and older adults performed either lexical decision (LDT) or naming tasks. A multiple regression procedure was used to predict priming based upon prime characteristics, target characteristics, and prime-target semantic similarity. Resu...

Previous research has examined the effects of emotional experience (i.e., the ease with which words evoke emotion information) in semantic categorization (SCT), word naming, and Stroop tasks (Newcombe et al., 2012; Siakaluk et al., 2014; Moffat et al., 2015). However, to date there are no published reports on whether emotional experience influences performance in the lexical decision task (LDT)...

This experiment examined how the characteristics of homophones and their mates influence homophone effects, as a function of task demands. Two types of homophones were presented: 1) low-frequency homophones with higher-frequency mates that are not animal names (e.g., maid--made), and 2) low-frequency homophones with mates that are, on average, of equivalent frequency and are animal names (e.g.,...

Previous studies have reported facilitatory effects of semantic richness on word recognition (e.g., Yap et al., 2012). These effects suggest that word meaning is an important contributor to lexical decision task (LDT) performance, but what are the effects of repeated LDT practice on these semantic contributions? The current study utilized data from the British Lexicon Project (BLP) in which 78 ...

We investigated whether and how sublexical units such as phonological syllables mediate access to the lexicon in French visual word recognition. To do so, two lexical decision task (LDT) experiments examined the nature of the syllabic neighbourhood effect. In Experiments 1a and b, the number of higher frequency syllabic neighbours was manipulated while controlling for the first bigram. The resu...