The specificity of pepsin, the major protease gastric digestion, has been previously investigated, but only regarding primary sequence protein substrates. present study aimed to consider in addition physicochemical and structural characteristics, at molecular sub-molecular scales. For six different proteins submitted vitro peptide bonds cleaved were determined from peptides released identified ...

Accurate statistical simulation and modeling are important for IC design. Different types of statistical simulation require different types of statistical models. In this paper a unified approach to statistical modeling and characterization is presented. Based on physical process parameters and propagation of variance, it allows modeling of process extremes, distributional modeling for Monte Ca...

The traditional method used to estimate the hydrodynamic performance of a ship uses either model test results or one many empirical methods and observe trend in fouling friction coefficient (ΔCF) over time. biggest weakness this is that as well here sometimes not well-fitted for full-scale due several reasons like scale effects and, therefore, may result an inaccurate prediction. Moreover, case...

Maren Hackenberga* , Marlon Grodda, Clemens Kreutza, Martina Fischerb, Janina Esinsb, Linus Grabenhenrichb, Christian Karagiannidisc & Harald Binderaa Institute of Medical Biometry and Statistics, Faculty Medicine Center, University Freiburg, Germany;;b Robert-Koch-Institut, Berlin, Germany;;c Department Pneumology Critical Care Medicine, Cologne-Merheim Hospital, ARDS ECMO Kliniken der Stadt K...