A DABCO-catalyzed domino reaction between methyleneoxindoles and allenoates which enables the direct synthesis of spirooxindoles is reported. This is the first example of a non-substituted allenoate to act as a four-carbon synthon in a tertiary amine-catalyzed reaction.

The deprotonation kinetics of the DEA--C02 and the DIPA-COZ zwitterions have been studied in aqueous blends of an&es at 298 K. Amine mixtures investigated were: DEA-TEA, DEA-MDEA. DEL-DMMEA, DEA-DEMEA, DIPA-TEA, DIPA-MDEA, DIPA-DMME~ DIPA-DEMEA. FOG each blend the zwitterion deprotonation constant of the additonal base present in solution (i.e. the tertiary amine) was determined. The observed d...

With 4-chloro-7-nitrobenzo-2, 1,3-oxadiazole (I), fluorescent derivatives of propoxyphene can be prepared, thus enabling quantitation of the drug in biological samples. This technique offers an acceptable alternative to gas chromatographic (1-5) or ultraviolet spectrophotometric (6, 7) procedures. Favorable aspects of the fluorometric technique are high sensitivity, specificity, potential for r...

Platinum and palladium dendrimer-encapsulated nanoparticles (DENs) were prepared within commercially available, fourth-generation, amine-terminated, poly(amidoamine) dendrimers (G4-NH2). The synthesis is carried out by selectively encapsulating metal complexes within the dendrimer and then reducing the resulting composite. Intradendrimer complexation requires control over the solution pH to pre...

Direct electrochemical synthesis of sulfonyl amidines from aliphatic amines and sulfonyl azides was realized with good to excellent yields. Traditional tertiary amine substrates were broadened to secondary and primary amines. The reaction intermediates were observed and a reaction mechanism was proposed and discussed.

By employing a chiral bifunctional thiourea-tertiary amine as catalyst, enantioselective Michael addition of a kojic acid derivative to nitro olefins was realised. The reactions afforded the products with good yields (up to 99%) in good enantioselectivities (up to 97% ee). In addition, the absolute configuration of one product was determined.

CO2-switchable multi-compartment micelles (MCMs) with a segregated corona formed by a purpose-designed ABC triblock copolymer are reported. They can be switched "on" and "off" when sequentially treated with CO2 and N2, due to the protonation-deprotonation of the tertiary amine groups along the polymer skeleton.