BACKGROUND AND OBJECTIVE Persistent Müllerian duct syndrome (PMDS) is a relatively rare form of 46,XY disorder of sex development caused by the failure of formation, release or action of anti-Müllerian hormone (AMH) in intrauterine life. In this report we describe a case diagnosed with PMDS with a novel homozygous mutation in the AMH gene. CASE REPORT A 4-month-old male presented with bilater...

Background: Buceng is a combination of plant of purwoceng (Pimpinella alpina Molk) and pasak bumi (Eurycomalongifolia Jack) that has been traditionally used to enhance adult male vitality. However, the mechanism of action of buceng has not been understood. This study was aimed to elucidate whether buceng could increasing Testosterone (Te), Luteinizing Hormone (LH), and Follicle Stimulating Horm...

the side effects associated with the usage of synthetic antidiabetic drugs make it imperative to search for alternative drugs from medicinal plants. therefore, this study was aimed at evaluating the α-amylase and α-glucosidase inhibitory potential of calotropis procera leaf, as well as its possible mode of inhibiting these enzymes. acetone, aqueous and ethanolic extracts of c. procera leaf was ...

Pendahuluan : Menopause adalah fase di mana organ reproduksi menurun, terutama fungsi ovarium, yang mengakibatkan penurunan hormon seperti estrogen, progesteron, dan testosteron. Keadaan ini menimbulkan berbagai masalah kesehatan pada akhirnya akan berdampak kualitas hidup. Untuk mengatasi hal ini, intervensi terapi latihan fisik direkomendasikan. Tujuan: Tujuan dari penelitian untuk menilai hi...

Merkezi sinir sistemi içerisinde nörotransmitter ve nöromodülatör etkiye sahip histamin, davranış durumunun, biyolojik ritmin, vücut ağırlığının, enerji metabolizmasının, termoregülasyonun, sıvı dengesinin, stresin üremenin düzenlenmesinde anahtar role sahiptir. Histaminin merkezi akut enjeksiyonlarının hipotalamo-hipofizer-gonadal (HPG) aks etkili olduğunu histaminin H1 H2 reseptör-lerinin bu ...