THE REDUCTION in metabolic rate effected by hypothermia constitutes the central tenet of traditional organ preservation. The antithesis of this approach is to provide for metabolic demand during normothermic preservation. This latter strategy has two potential benefits. First, if metabolic requirements are met during preservation, then longer preservation with better posttransplant function may...

Persufflation (PSF; gaseous oxygen perfusion) is an organ preservation technique with a potential for use in donor heart preservation. Improved heart preservation with PSF may improve outcomes by maintaining cardiac tissue quality in the setting of longer cold ischemia times and possibly increasing the number of donor hearts available for allotransplant. Published data suggests that PSF is able...

Currently, nanotechnology represents an important tool and an efficient option for extending the shelf life of foods. Reducing particle size to nanometric scale gives materials distinct and improved properties compared to larger systems. For food applications, this technology allows the incorporation of hydrophilic and lipophilic substances with antimicrobial and antioxidant properties that can...

PURPOSE To present a case of embryonal rhabdomyosarcoma of the intrinsic laryngeal musculature and discuss the treatment of this rare tumor. METHODS AND MATERIALS A 45year-old male presented with an eleven month history of hoarseness. A mass of the posterior glottis was noted on fiberoptic laryngoscopy. Computed tomography indicated a 1.5×2.5cm laryngeal mass without cartilage involvement. Di...

While organ preservation with nonextirpative surgery, radiotherapy, and frequently, chemotherapy has become a favored strategy in the treatment of many cancers, bladder preservation for patients with invasive disease remains controversial. The standard treatment for muscle-invasive bladder cancer in the United States is still radical cystectomy with pelvic lymph node dissection. An alternative ...

Subtyping occurs when atypical examples are excluded from consideration in judging a category. In three experiments, we investigated whether subtyping can influence category learning. In each experiment, participants learned about a category where most, but not all, of the exemplars corresponded to a theme. The category structure included a subtyping dimension, which had one value for theme-con...

Internationally organisations are struggling with a general disregard for the importance of taking proper care of digital artefacts. The purpose of this paper is to provide insight into the background for developing a digital preservation strategy for a research organization such as the Council for Scientific and Industrial Research (CSIR). The CSIR’s shift to a predominantly digital environmen...

The Bibliothèque nationale de France has developed its trusted digital repository, SPAR (Scalable Preservation and Archiving Repository), as a data-first system. This implies having fully described collections, through use of metadata standards in the information packages, such as METS, PREMIS, MIX or textMD, in a way that will make sense given the diversity of our documents. The need for full ...

Correspondence: Kenneth Storey Departments of Biology and Chemistry, Carleton University, 1125 Colonel By Drive, Ottawa, ON, Canada K1S 5B6 Tel +1 613 520 3678 Fax +1 613 520 3749 email [email protected] Abstract: To survive under harsh environmental conditions many organisms retreat into hypometabolic states where metabolic rate may be reduced by 80% or more and energy use is repriori...