This paper contends that establishing a central theme in the information systems curriculum is important to program stakeholders. An analysis of the IS 2010 Curriculum Guidelines (Topi et al., 2010) reveals that the systems approach can be an effective integrating theme throughout the IS curriculum. This paper concludes that the systems approach to problem solving, applied at different levels o...

As a grammatical device, Theme-Rheme structure plays an important role in organizing and analyzing discourse. Theme Progression patterns (hereinafter called TP patterns) are significant method of the analysis of textual cohesion and organization. Based on linguist Danes’ theory about TP patterns, this paper tries to present a contrastive analysis of the texts of consecutive interpretation in En...

The first half of this paper constitutes the lecture given at the conference meeting, and contains some general discussion and a survey of the area. The second half gives proofs of some new results that were mentioned but not given. The reader interested only in these, (the theorems of the abstract) can turn to §2.2 Theorem 12 and §2.3. We assume at those points a working familiarity with fine ...

In recently years, high-throughput experimental techniques such as microarray, RNA-Seq and mass spectrometry can detect cellular moleculars at systems-level. These kinds of analysis generate huge quantitaties of data, which need to be given a biological interpretation. A commonly used approach is via clustering in the gene dimension for grouping different genes based on their similarities(Yu et...

In addition to their roles in organizing the actin cytoskeleton, members of the Rho family of GTP-binding proteins have recently been implicated in a plethora of other functions, including the activation of kinase cascades and transcription factors, and the control of endocytosis and secretion. Alongside this expansion is proposed functions has been the identification of multiple target protein...