BACKGROUND The outcome of patients with corrected transposition of the great arteries (CTGA) is variably affected by associated intracardiac defects, tricuspid valve competence, and systemic right ventricular (RV) function. The relative importance of these factors in long-term outcome has not been evaluated. METHODS AND RESULTS Since 1958, 40 patients with CTGA were studied to determine risk ...

. 9 lnt:J-oo.uction I •••••••••••••••••••••••••••••••••••••••••••••••••••••••• I ••••••••••• 10 Discussion and Results 14 I Conclusions.... I..................................................................................................................... 28 Expe.rimental Ill....... .. 30 tI tI I t1 , •• •••• Appendix A: Publication in Tetrahedron Letters 2002 37 References 3S Appendix B: Sp...

INTRODUCTION Changes in combination antiretroviral therapy (cART) throughout childhood challenge the continuity of paediatric HIV treatment. This study aimed to evaluate the prevalence of treatment interruption (TI), including lamivudine (3TC) monotherapy, and the relationship of TI to virologic and immunologic parameters in HIV-infected paediatric patients. METHODS Nested within a prospectiv...

OBJECTIVES This study evaluated cytocompatibility and osseointegration of the titanium (Ti) implants with resorbable blast media (RBM) surfaces produced by grit-blasting or XPEED(®) surfaces by coating of the nanostructured calcium. MATERIAL AND METHODS Ti implants with XPEED(®) surfaces were hydrothermally prepared from Ti implants with RBM surfaces in a solution containing alkaline calcium....

TI significantly reduced HbA1c by20.8% (29.0 mmol/mol) from a baseline of 8.3% (66.8 mmol/mol) compared with TP 20.4% (24.6 mmol/mol) (treatment difference 20.4% [95% CI 20.57, 20.23]; P < 0.0001). More TI-treated subjects achieved an HbA1c £7.0% (53.0 mmol/mol) (38% vs. 19%; P = 0.002). Mean fasting plasma glucosewas similarly reduced in both groups. Postprandial hyperglycemia, based on 7-poin...

Implant surfaces should be modified to achieve excellent cell compatibility as well as antibacterial activity. Our previous study demonstrated that titanium plates anodized by being discharged in NaCl (Ti-Cl) exhibited high antibacterial activity. Since Ti-Cl was prepared with a NaCl solution, we hypothesized that Ti-Cl would exhibit low toxicity toward cells. The aims of this study were to cha...

F-Ti-MWW was post-synthesized by implanting fluorine species into a Ti-MWW framework through an acid treatment process in the presence of ammonium fluoride. The effects of NH4F addition amount, acid treatment temperature and precursor Ti content were investigated on the incorporation of F species, the zeolite structure and the coordination sites of Ti. Fluorine-implanting improved the surface h...

BACKGROUND The timely diagnosis of presence or absence of reperfusion injury after cardiac operation is critical for the patient's outcome. Whether transesophageal echocardiography (TEE) acquisition of regional grayscale intensity (TI), velocity, and displacement (D) after cardiac operation can discriminate between patients with ST-segment elevation ischemic reperfusion injury (STEIRI) and norm...

The recent progress in the field of Ti:Er:LiNbO3 waveguide lasers with emission wavelengths in the range 1530 nm < λ < 1603 nm is reviewed. After a short discussion of the relevant fabrication methods concepts and properties of different types of lasers with grating resonator, acoustooptically tunable Fabry Pérot type lasers and new ring laser structures are presented. key words: integrated opt...

This short feature describes a project to create an online opera which deploys a new web technology, the Syzygy Surfer, developed in the Institute of Creative Technologies (IOCT) at De Montfort University. The project is a collaboration between the IOCT and The Opera Group.