BACKGROUND Side-to-side (STS) neurorrhaphy can be performed distally to ensure timely end-organ innervation. It leaves the distal end of the injured nerve intact for further reconstruction. Despite encouraging clinical results, only few experimental studies have been published to enhance the regeneration results of the procedure. We examined the influence of different size epineural windows and...

Background. Lower extremity nerve injuries caused by wounds are often not noticed immediately after trauma. The purpose of this article was to analyze the localization of penetrating injuries to the nerves, the mechanism and extent of the lesions, and the microsurgical techniques used. The diagnostic and therapeutic basics in penetrating injuries of lower extremity nerves are also described. Ma...

BACKGROUND There is limited appreciation of the risks and benefits of the few salvage treatment options available for inadequate motor function following incomplete spontaneous recovery or surgical repair of major peripheral nerve injuries. The lack of a reliable and economical animal model has hindered laboratory investigation into this difficult clinical problem. We propose a straightforward ...

Kido, Aiko, Naofumi Tanaka, and Richard B. Stein. Spinal reciprocal inhibition in human locomotion. J Appl Physiol 96: 1969–1977, 2004. First published December 5, 2003; 10.1152/ japplphysiol.01060.2003.—The purpose of this paper was to study spinal inhibition during several different motor tasks in healthy human subjects. The short-latency, reciprocal inhibitory pathways from the common perone...

Reactive and adaptive changes in mechanically uninjured nerves during fracture healing have not been studied previously although the status of innervation is important for bone union and functional recovery. This study explores whether subclinical nerve fibre degeneration occurs in mechanically uninjured nerves in an animal fracture model and to quantify its extent and functional significance. ...

Persistent sciatic vein is considered a relatively rare anatomical finding, commonly associated with the Klippel-Trenaunay-Weber syndrome. We report case of large unilateral persistent in right lower limb an adult male cadaver, identified during routine dissection. The size was comparable to nerve and it originated from union posterior tibial veins at distal end popliteal fossa. It ascending pa...

BACKGROUND Tibial mononeuropathy due to compression by a synovial cyst is uncommon with fewer than 10 cases reported in the literature. METHOD Case Study. RESULTS Tibial motor mononeuropathy with focal conduction block between the popliteal fossa and ankle was identified by electrophysiological testing. Magnetic resonance imaging and surgical exploration identified a synovial cyst compressi...

RATIONALE It is challenging to visualize and reduce a posterolateral tibial plateau fracture through an anterolateral approach as the tibial plateau fragments are often covered by the fibular head and ligamentous structures. PATIENT CONCERNS In this case report, we describe a patient with a depression fracture of the posterolateral quadrant combined with a split fracture of the posteromedial ...

BACKGROUND Distal neuropathy is part of the clinical phenotype in most males with the fragile X-associated tremor/ataxia syndrome (FXTAS) caused by the 55 to 200 CGG repeat expansion. METHODS We performed nerve conduction studies in 16 male carriers with FXTAS, 11 non-FXTAS carriers, and 11 control subjects and assessed the outcomes with respect to the fragile X mental retardation 1 genotype ...

Damage to peripheral nerve tissue may cause loss of function in both the nerve and the targeted muscles it innervates. This study compared the repair capability of engineered nerve conduit (ENC), engineered fibroblast conduit (EFC), and autograft in a 10-mm tibial nerve gap. ENCs were fabricated utilizing primary fibroblasts and the nerve cells of rats on embryonic day 15 (E15). EFCs were fabri...