Conventional oestrogen-based hormone therapy (HT) increases the incidence of breast pain and tenderness, mammographic density and the risk of breast cancer. Combined oestrogen plus progestogen therapy (EPT) increases the risk of breast cancer to a greater degree than oestrogen alone (ET). Attention must therefore be focused on identifying women at risk of breast cancer or on producing a HT that...

jugated equine estrogens effects on coronary artery atherosclerosis and bone density of postmenopausal monkeys. J Clin Endocrinol Metab 2001;86:5396–5404. 6. Mikkola TS, Anthony MS, Clarkson TB, St Clair RW. Serum cholesterol efflux in postmenopausal monkeys treated with tibolone or conjugated estrogens. Metabolism 2002;51:523–530. 7. von Eckardstein A, Schmiddem K, Hövels A, Gulbahce E, Schule...

OBJECTIVE To describe changes in prescription of hormone replacement therapy (HRT) in Asturias (Spain) after the publication of the results of the Women's Health Initiative and the Million Women Study and following the recommendations of the Spanish Drugs Agency to women and prescribers (2004-2005). METHODS We performed a quasiexperimental study with no control group. The data used consisted ...

............................................................................................ 9 INTRODUCTION...................................................................................... 11 REVIEW OF THE LITERATURE.................................................................. 13 Menopause............................................................................... 13 Cardiovascular...