Anti-oxidant effects of propofol (2, 6-diisopropylphenol) were evaluated agains carbon tetrachloridet CCl4 -induced oxidative stress in rat liver. 30 male rats were equally divided in to 6 groups (5 rats each). Group I (control), while Group II was given CCl4 (3 mL /Kg/day, IP). Animals of Groups III received only propofol (10 mg/Kg/day, IP). Group IV was given propofol+ CCl4. Group V was admin...

We studied the influence of vitamin E on intramuscular collagen characteristics and on metacarpal growth plate evolution in suckling lambs. Twenty-four 5-d-old Ile de France suckling male lambs were divided into four equal weight groups, and weekly i.m. injections of DL-alpha-tocopheryl acetate (Control group, 0 IU; Group 1, 625 IU; Group 2, 1,000 IU; and Group 3, 1,500 IU) were given until the...

Necrotic liver degeneration is produced in rats by diets deficient in vitamin E, cystine, and Factor 3 (1). During the latent phase of the disease, several weeks before the onset of acute hepatic necrosis, a defect in oxidative metabolism has been demonstrated in livers of animals on such diets. oxygen consumption of histologically unaffected liver slices breaks down after a brief initial perio...

Abstract The study objective was to evaluate the effect of two fat sources and graded levels vitamin E (VE) supplementation on tissue fatty acid profile, VE concentrations, immune capacity antioxidant plasma tissues pigs at heavy slaughter weight (150 kg). A total 48 individually-fed (24 barrows, 24 gilts; 28.44 ±2.69 kg) were randomly assigned 8 dietary treatments in a 2 × 4 factorial arrangem...

Recent work has indicated that evidence supporting a role for tocopherol in electron transport should be re-evaluated. The direct demonstration of the inhibitory nature of solvents on enzymes of the respiratory chain (1) and nonspecific restoration of this activity by various lipids (2, 3) are the major objections to studies which employed isooctane extraction. However, other evidence based on ...

Natural vitamin E consists of four different tocopherol and four different tocotrienol homologues (a,b, c, d) that all have antioxidant activity. However, recent data indicate that the different vitamin E homologues also have biological activity unrelated to their antioxidant activity. In this review, we discuss the anti-inflammatory properties of the two major forms of vitamin E, a-tocopherol ...

Recent work has indicated that evidence supporting a role for tocopherol in electron transport should be re-evaluated. The direct demonstration of the inhibitory nature of solvents on enzymes of the respiratory chain (1) and nonspecific restoration of this activity by various lipids (2, 3) are the major objections to studies which employed isooctane extraction. However, other evidence based on ...

Relative vitamin E status of pigs fed natural or synthetic vitamin E was evaluated based on serum and tissue alpha-tocopherol concentrations. Individually fed finishing gilts at a BW of 70.5 kg (n = 24) were allotted to dietary treatments based on initial BW. The 5 dietary treatments consisted of a positive control diet using synthetic vitamin E acetate (Syn E Ac) supplemented at 22 mg/kg, and ...