A new general algorithm for optimization of potential functions for protein folding is introduced. It is based upon gradient optimization of the thermodynamic stability of native folds of a training set of proteins with known structure. The iterative update rule contains two thermodynamic averages which are estimated by (generalized ensemble) Monte Carlo. We test the learning algorithm on a Len...

BACKGROUND To study phacoemulsification probe shaft/wound and corneal surface/tip temperatures in vivo during longitudinal, torsional and combined phacoemulsification modes and their relationship to machine parameters. DESIGN This was a prospective study at Chaithanya Eye Hospital and Research Institute, Trivandrum, India (tertiary). PARTICIPANTS Twenty-two eyes of 22 patients were randomiz...

This paper reports the design and simulation of a 4 mm² double differential torsional MEMS accelerometer based on a double-beam configuration. Based on the structure of conventional torsional accelerometers, normally composed of one pair of proof masses and one torsional beam, this work explores the double differential configuration: a torsional accelerometer with two pairs of unbalanced proof ...

In this paper, we consider linear dynamics subject to a distributed state-dependent delay and a pointwise input-delay. We propose a prediction-based controller which exponentially stabilizes the plant. The controller design is based on a backstepping approach where delays are reformulated as hyperbolic transport PDEs. Infinity-norm stability analysis of the corresponding closed-loop system is a...

Harms tangent screen, a subjective measurement method of three-dimensional binocular alignment, was compared with search coil recording. Twenty-three patients with unilateral trochlear nerve palsy were measured in nine gaze positions. The two methods correlated best for the horizontal gaze deviation, the vertical gaze deviation, and the vertical incomitance, but there was no correlation for the...

purpose: to compare corneal endothelial cell features after cataract surgery performed using fixed torsional or conventional (pulse) ultrasound mode. methods: in this randomized comparative study, 60 eyes were randomly and equally divided into two groups of torsional or longitudinal mode phacoemulsification. all surgeries were performed by an experienced surgeon, and the outcomes were evaluated...

This paper describes the Lyapunov-based force control suppressing the coupled bending and torsional vibrations of a one-link flexible arm with a rigid tip body. On the basis of the distributed parameter model, the output feedback control law is constructed using Lyapunov method, and the asymptotic stability of the closedloop system is proved. The proposed controller consists of the PD feedback ...

We propose a coherent, strong-field approach to control the torsional modes of biphenyl derivatives, and develop a numerical scheme to simulate the torsional dynamics. By choice of the field parameters, the method can be applied either to drive the torsion angle to an arbitrary configuration or to induce free internal rotation. Transient absorption spectroscopy is suggested as a probe of torsio...

Successful replacement of hips is the only solution for severe degenerative diseases such as osteoarthritis (Bird, 1995). During cemented fixation of the acetabular cup, anchorage holes are drilled in the acetabulum, then cement is introduced and pressurised to create cement pegs within the anchorage holes. During physiological activities, the bone cement interface of the acetabulum experiences...

In this paper, the effect of Static VAr Compensator (SVC) parameters on the nonlinear interaction of steam power plant turbine-generator set is studied using the Modal Series (MS) method. A second order representation of a power system equipped with SVC is developed and then by MS method the nonlinear interaction of torsional modes is assessed under various conditions and the most influencing f...