Allergic fungal rhinosinusitis (AFRS) is characterized by the growth of fungi, mostly Aspergillus sp., in the paranasal sinuses together with the formation of nasal polyps, peanut-butter like “allergic mucin” with fungal hyphae and typical CT-findings, as well as increased serum total IgE and Aspergillus-specific IgE concentrations. We here hypothesize that the increase in serum total IgE is ca...

IgE, and atopy. Results: We measured the total serum IgE of 155 children. The number of obese and normal weight children with family history of atopic disease who had high level of total serum IgE were 30 and 25 respectively, whereas these children who had normal level of total serum IgE were 6 and 15 respectively [OR 1⁄4 1.9 (95% CI 0.9-3.9)]. On the other hand, obese and normal weight childre...

A B S T R A C T Total and filaria-specific immunoglobulin E (IgE) levels were studied in cord blood from infants born in Madras, India, where filariasis and intestinal helminth infections are highly endemic. Increased total IgE levels were observed in 82% of 57 cord sera tested (geometric mean 12.6 ng/ml; range 1-1,900 ng/ml). 33 of these sera also contained IgE antibodies specific for flarial ...

Methods We examined 50 formulae fed infants 1-12 months old with food allergy. The examination included a collection of allergy history, clinical evaluation and specific methods – the measurement of the coprofiltrate levels of total IgE and allergen-specific IgE to the cow milk protein and casein. The level of total IgE, cow and goat milk proteins IgE allergen-specific antibodies in coprofiltra...

BACKGROUND Immunoglobulin (Ig) E is well-known to play a critical role in allergic diseases. We investigated the association between longitudinal change in total IgE level and the asthma control in patients with adult asthma. METHODS For this retrospective study, 154 patients with asthma aged 21-82 years were recruited from the allergy and pulmonary units of the Showa University Hospital. Dat...

M to 2.8 x 10'0/M, averaging 7.7 x 109/M. Unexpectedly, the total number of IgE receptors/basophil was closely related to the serum IgE level. (r8 = 0.92, P < 0.001). Thus, either there is genetic association between serum IgE and the number of basophil IgE receptors, or, more likely, the receptor number is modulated by the serum IgE concentration.

BACKGROUND House dust mites (HDMs) are important sources of indoor allergens. Seventeen components have been identified from Dermatophagoides pteronyssinus (Der p). OBJECTIVE Our aim was to define the prevalence of specific IgE to components of Der p in Korea and investigate the clinical features of them in children with allergic disease. METHODS We performed a prospective evaluation of 80 ...

While serum immunoglobulin E (IgE) concentration has been shown to be related to allergic disease, there have been few studies of the natural history of IgE development in young children. This study compared total and allergen-specific serum IgE concentrations, by gender, from birth through 4 years of age using a population-based cohort of normal children followed from 1987 to 1993. Subjects we...

We studied Hymenoptera stings in 72 pest-control operators without any previous systemic reactions to Hymenoptera stings, and investigated their venom-specific IgE levels in serial specimens collected over one year. At the initial evaluation, venom-specific IgE was present in 25 (34.7%) of 72 pest-control operators, and venom-specific IgE titer significantly decreased as the time interval from ...

Several studies have shown that the presence of IgE antibodies to house dust mites (HDM), particularly Dermatophagoides pteronyssinus (Dpt), is an important risk factor for asthma. Allergen immunotherapy is indicated for patients with IgE antibodies to clinically relevant allergens. The aims of this study were to analyze the levels of specific serum IgE to Der p 1 and Der p 2 allergens in mite-...