Two different gas chromatography coupled to quadrupole-time of flight mass spectrometry (GC-QTOF-MS) methodologies were carried out for the analysis of phytosterols and tocopherols in the flesh of three mango cultivars and their by-products (pulp, peel, and seed). To that end, a non-polar column ((5%-phenyl)-methylpolysiloxane (HP-5ms)) and a mid-polar column (crossbond trifluoropropylmethyl po...

BACKGROUND The effect of α-tocopherol or simvastatin treatment on antioxidant defense in liver of old rats was investigated. METHODS Endogenous thiobarbituric acid reactive substances (TBARS) and total nitrite/nitrate (NO(2)/NO(3)) levels as well as non-enzymatic glutathione (GSH) and enzymatic antioxidants [glutathione-S-transferase (GST), superoxide dismutase (SOD), glutathione peroxidase (...

objectives: potato (solanum tuberosum l.), as a whole food, contains high levels of vitamins and important antioxidants including phenolic acids, carotenoids and flavonoids. the objective of this study was to determine the total phenolic content and antioxidant activities of three common potatoes (solanum tuberosum) cultivars in iran i.e., savalan, agria and sante. materials and methods: phenol...

The effect of dietary RRR-g-tocopherol supplementation on serum and tissue aand g-tocopherol concentrations was studied in vitamin-E-deficient rats fed diets containing adequate levels of RRR-a-tocopherol and graded levels of RRR-g-tocopherol over a 60 day period. Feeding rats with a RRR-a-tocopherol-supplemented diet induced in forebrain, sciatic endoneurium, skeletal muscle, heart and liver a...

BACKGROUND Some studies have shown potential benefit of vitamin E on platelet function, but several clinical trials failed to show improved cardiovascular outcome with alpha-tocopherol supplementation. Gamma-tocopherol, a major dietary form of vitamin E, may have protective properties different from those of alpha-tocopherol. OBJECTIVE We compared the effects of supplementation with alpha-toc...

BACKGROUND Alpha-Tocopherol and gamma-tocopherol are the two major forms of vitamin E in human plasma and the primary lipid soluble antioxidants. The dietary intake of gamma-tocopherol is generally higher than that of alpha-tocopherol. However, alpha-tocopherol plasma levels are about four fold higher than those of gamma-tocopherol. Among other factors, a preferential cellular uptake of gamma-t...

Background: Studies on the cholesterol lowering activity of tocotrienols have yielded mixed results, with some showing cholesterol lowering effect while some showing no activity. Aim: A randomized, doubleblind, parallel group study was conducted to investigate the cholesterol lowering activity of tocotrienols. Methods: Thirtytwo hypercholesterolemic subjects were randomly assigned to orally r...

Tocopherols are plant-derived isoprenoids with potent antioxidant activity, which have been implicated in the tolerance of plants to different stresses. However, tocopherol accumulation and biosynthesis fruit, their potential implication postharvest chilling injury (CI), has scarcely studied. Therefore, this work, we investigated peel mandarin fruit three cultivars contrasting susceptibility CI...

The aim of this study was to determine the effects of dietary antioxidant supplementation with alpha-tocopherol and alpha-lipoic acid on cyclosporine-induced alterations to erythrocyte and plasma redox balance, and cyclosporine-induced endothelial and smooth muscle dysfunction. Rats were randomly assigned to either control, antioxidant, cyclosporine or cyclosporine + antioxidant treatments. Cyc...

OBJECTIVE Osteoporosis increases the risk of bone fractures and may impair fracture healing. The aim of this study was to investigate whether alpha-tocopherol can improve the late-phase fracture healing of osteoporotic bones in ovariectomized rats. METHOD In total, 24 female Sprague-Dawley rats were divided into three groups. The first group was sham-operated, and the other two groups were ov...