Exposure of health care workers to antineoplastic drugs and subsequent adverse health effects is still an open issue. Very little has been studied on the extent of occupational exposure and handling conditions of antineoplastic drugs in Iran. We aimed to determine cyclophosphamide and ifosfamide concentrations in the urine samples of oncology healthcare workers. In addition, we assessed workpla...

Background: Acute appendicitis is the most common surgical emergency of the childhood. Its diagnosis is really challenging. A constellation of through history taking, physical examination, radiographic investigations, and laboratory analysis should be used to balance the risk of delayed operative intervention against the removal of a normal appendix. Here a case with misdiagnosis of acute app...

Tropical fresh water stingrays have become quite popular among amateur and professional aquarists due to their attractive appearance. However, the species may have a high life-threatening potential. Stingray intoxication is rare in Eastern Europe and there is no specific antivenin available. We present the first case of “rayism” – envenomation caused by sp. Reticulatus in Eastern Europe. The pa...

Article history: Received on: 29/12/2015 Revised on: 21/01/2016 Accepted on: 05/02/2016 Available online: 28/05/2016 Adverse drug reaction is defined by the WHO as a response to a medicinal product which is noxious and unintended, and which occurs at doses normally used in man for prophylaxis, diagnosis, therapy of disease or for the modification of physiologic function. The term Pharmacovigila...

At the beginning of the twentieth century it was common to administer poisons to get rid of unwanted people, or simply to ingest poisons by accident. The science of forensic toxicology was not well developed yet, and many death certificates were issued without properly identifying the cause of death. Pulitzer Prize–winning science writer Deborah Blum has created a larger story structured like a...

Acquisition and analysis of environmental data are essential to the quality, safety and health of human life, and typically consist of heterogeneous, multivariate, and spatio-temporal information collected from different resources. In the United States, the Environmental Protection Agency (EPA) is responsible for protecting human health and the environment; it does so by developing and enforcin...

The laboratory toxicologist is frequently faced with the challenge of selecting appropriate vehicles or developing utilitarian formulations for use in in vivo nonclinical safety assessment studies. Although there are many vehicles available that may meet physical and chemical requirements for chemical or pharmaceutical formulation, there are wide differences in species and route of administrati...

Information on drug toxicity is used primarily by three segments of the health care industry: the consumer or patient, healthcare practitioners, and research and development (R&D) scientists in the pharmaceutical industry. The major focus of both consumers and health care practitioners is the provision of suitable information for the safe use of drugs for both individuals and specific patient p...

Medical toxicology is the clinical specialty that treats toxic effects of substances, for example, an overdose, a medication error, or scorpion sting. The volume toxicological knowledge and research has, as with other medical specialties, outstripped ability individual clinician to entirely master stay current it. application machine learning/artificial intelligence (ML/AI) techniques challengi...