Nigella sativa seeds (NS) has been used traditionally for various illnesses. The most abundant and active component of NS is thymoquinone (TQ). Animal studies have shown that NS and TQ may be used for the treatment of diabetes-induced osteoporosis and for the promotion of fracture healing. The mechanism involved is unclear, but it was postulated that the antioxidative, and anti-inflammatory act...

AIM To evaluate the role of reactive oxygen species in the pathogenesis of acute ethanol-induced gastric mucosal lesions and the effect of Nigella sativa L oil (NS) and its constituent thymoquinone (TQ) in an experimental model. METHODS Male Wistar albino rats were assigned into 4 groups. Control group was given physiologic saline orally (10 mL/kg body weight) as the vehicle (gavage); ethanol...

objective(s):acrylamide (acr) has broad applications in different industries. it also forms in food during heating process. oxidative stress has a critical role in acr-induced neurotoxicity in both in vitro and in vivo models; therefore, the aim of the current study was the evaluation of effects of thymoquinone, the main constituent of volatile oil from nigella sativa seeds in acr-induced neuro...

A subspace bitrade of type Tq(t, k, v) is a pair (T0, T1) of two disjoint nonempty collections (trades) of k-dimensional subspaces of a v-dimensional space F v over the finite field of order q such that every t-dimensional subspace of V is covered by the same number of subspaces from T0 and T1. In a previous paper, the minimum cardinality of a subspace Tq(t, t + 1, v) bitrade was establish. We ...

We have performed this study to investigate the modulatory effect of thymoquinone (TQ), the Nigella sativa active compound, on erythrocyte lipid peroxidation and antioxidant status during 1,2-dimethylhydrazine- (DMH-) induced colon carcinogenesis after initiation in male Wistar rats. Rats exposed to DMH showed an increase of malondialdehyde and conjugated diene levels, and an augmentation of en...

The lifetime of the luminous phase of quasars is constrained by current observations to be 10 ∼< tQ ∼< 10 years, but is otherwise unkown. We model the quasar luminosity function in detail in the optical and X–ray bands using the Press–Schechter formalism, and show that the expected clustering of quasars depends strongly on their assumed lifetime tQ. We quantify this dependence, and find that ex...

The study of core partitions has been very active in recent years, with the study of ps, tq-cores – partitions which are both sand t-cores – playing a prominent role. A conjecture of Armstrong, proved recently by Johnson, says that the average size of an ps, tq-core, when s and t are coprime positive integers, is 1 24ps ́1qpt ́1qps` t ́1q. Armstrong also conjectured that the same formula gives the...

nigella sativa seeds have wide therapeutic effects and have been reported to have significant effects against many ailments such as skin diseases, jaundice, gastrointestinal problems, anorexia, conjunctivitis, dyspepsia, rheumatism, diabetes, hypertension, intrinsic hemorrhage, paralysis, amenorrhea, anorexia, asthma, cough, bronchitis, headache, fever, influenza and eczema. thymoquinone (tq) i...

Thymoquinone (TQ), bioactive molecule of black cumin, has antioxidant and neuroprotective effects. TQ’s hypoglecemic effect while applied prenatally is reported. This study aimed to find the TQ dose with maximum minimum side effects in valproic acid (VPA) induced oxidative stress. Pregnant Wistar rats were injected i.p. 400 mg/kg/ml VPA on embryonic day 12.5 (E12.5). Repeated groups from E11.5-...

Black seed (Nigella sativa) is considered as a biological response modifier. Thymoquinone (TQ) is the bioactive and the most abundant constituent of the volatile oil of this seed which has been shown to possess anti-inflammatory, antioxidant and anti-neoplastic effects. In this study, the effect of TQ on HepG2 cell line was investigated in an attempt to identify its potential mechanism of actio...