To understand dynamic developmental processes, living tissues have to be imaged frequently and for extended periods of time. Root development is extensively studied at cellular resolution to understand basic mechanisms underlying pattern formation and maintenance in plants. Unfortunately, ensuring continuous specimen access, while preserving physiological conditions and preventing photo-damage,...

Liquid sloshing is a common industrial problem affecting not only the dynamics of flow inside the container, but also of the downstream systems being fed from the container. This paper deals with the application of Computational Fluid Dynamics (CFD) for analyzing the possible effect of oil sloshing in compressors used in underground rail application on the continuous supply of lubricant to the ...

Cytoplasmic dyneins drive microtubule-based, minus-end directed transport in eukaryotic cells. Whereas cytoplasmic dynein 1 has been widely studied, IFT dynein has received far less attention. Here, we use fluorescence microscopy of labelled motors in living Caenorhabditis elegans to investigate IFT-dynein motility at the ensemble and single-molecule level. We find that while the kinesin compos...

I develop and estimate a general equilibrium model for the term structures of nominal and real interest rates in the UK that incorporates Markov-switching. The model allows for nonneutralities, nonlinear dynamics, and ßexibility in the dynamics of the risk premia features that are all present in the data. I use the model to assess how accurately the term structure reßects changing expectations ...

Numerical simulation is replacing experimentation as a means to gain insight into complex physical phenomena. Analyzing the data produced by such simulations is extremely challenging, given the enormous sizes of the datasets involved. In order to make efficient progress, analyzing such data must advance from current techniques that only visualize static images of the data, to novel techniques t...

We present an algorithm for finding the probabilities of rare events in nonequilibrium processes. The algorithm consists of evolving the system with a modified dynamics for which the required event occurs more frequently. By keeping track of the relative weight of phase-space trajectories generated by the modified and the original dynamics one can obtain the required probabilities. The algorith...

Determining the relative contributions of intrinsic and extrinsic processes to the regulation of biological populations has been a recurrent ecological issue. Recent discussions concerning ecosystem "regime shifts" again raise the question of whether population fluctuations are mainly controlled by external forcing. Results of nonlinear time series analyses indicate that pelagic populations typ...