The purpose of this study was to examine the effect of 0-50 micromol/L trans-10, cis-12 conjugated linoleic acid (CLA) and cis-9, trans-11 CLA isomers on lipid and glucose metabolism in cultures of differentiating 3T3-L1 preadipocytes. Specifically, we investigated the effects of 6 d of CLA treatment on the following: 1) (14)C-glucose and (14)C-oleic acid incorporation and esterification into l...

5,6-trans-AA (5,6-TAA, where TAA stands for trans-arachidonic acid) is a recently identified trans fatty acid that originates from the cis-trans isomerization of AA initiated by the NO2 radical. This trans fatty acid has been detected in blood circulation and we suggested that it functions as a lipid mediator of the toxic effects of NO2. To understand its role as a lipid mediator, we studied th...

BACKGROUND High consumption of trans fat has been linked to the risk of coronary heart disease (CHD). We assessed the hypothesis that higher trans fatty acid contents in erythrocytes were associated with an elevated risk of CHD in a nested case-control study among US women. METHODS AND RESULTS Blood samples were collected from 32,826 participants of the Nurses' Health Study from 1989 to 1990....

Trans unsaturated fatty acids in humans may be originated both from dietary supplementation and an endogenous free-radical-catalyzed cis−trans isomerization of acid residues naturally occurring cis lipids. The latter process affords geometrical isomers the polyunsaturated mono-trans were demonstrated to connected with stress conditions living organisms. Synthesis is useful for analytical biolog...

An isomeric mixture of linoleic acid hydro peroxides, 13-hydroperoxy-cis9 trans-II-octadecadienoic acid (79%) a~d 9-hydroperoxy-eis-12,trans-IO-octadecadienoic acid (21 %), was decomposed homolytically by Fe(I!) in an ethanolwater solution. In one series of experiments, the hydroperoxides were decomposed by catalytic concentrations of Fe (II). The 10.5 M Fe(III) used to initiate the decompositi...

BACKGROUND Trans-fatty acids (TFAs), unsaturated fats with at least one double bond in the Trans configuration, are industrially formed in large quantities when vegetable oils are partially hydrogenated. This study was undertaken to quantify the amounts of the common fatty acids in several commercial oils marketing in Iran. METHODS The most consumed commercially available brands of vegetable ...

The addition of co-solvent on in situ trans esterification was considered as one method to improve the extractive process and increase yield biodiesel from microalgae. In this study, with using microwave studied for improving performance produced compared without addition. optimal reaction conditions (ratio microalgae methanol 1:15 w /v; 30 ml % H2SO4) at 50 min time, Fatty Acid Methyl Ester (F...

BACKGROUND Intake of trans fatty acids is associated with increased risk of coronary heart disease. Whether different classes of trans fatty acids show similar associations is unclear. We previously reported an association of sudden cardiac death with red cell membrane trans-18:2 but not trans-18:1 fatty acids. To extend these findings, we investigated the associations of plasma phospholipid tr...

Background—Intake of trans fatty acids is associated with increased risk of coronary heart disease. Whether different classes of trans fatty acids show similar associations is unclear. We previously reported an association of sudden cardiac death with red cell membrane trans-18:2 but not trans-18:1 fatty acids. To extend these findings, we investigated the associations of plasma phospholipid tr...