The fatty acid composition of serum cholesteryl esters is used as a qualitative biomarker of fatty acid intake, but quantitative data are scarce. Between 1987 and 1992, the authors fed various fatty acids in four controlled trials to 232 healthy Dutch volunteers and measured the proportion of fatty acids in participants' cholesteryl esters. Each 10% of energy fed as linoleic acid (18:2) raised ...

The effects of saturated and unsaturated fatty acids on the growth of Bordetella pertussis strain 114 in defined medium were tested. Individual fatty acids were found to be either inhibitory or stimulatory to growth, depending on concentration. Myristic (C14), pentadecanoic (C15), and palmitic (C16) acids were the most inhibitory saturated fatty acids tested. B. pertussis 114 was extremely sens...

KD115 (ol1), an unsaturated fatty acid auxotroph of S. cerevisiae, was grown in a semi-synthetic medium supplemented with 3.3 x 10(-4) M palmitoleic (cis 16:1) or palmitelaidic (trans 16:1) acids. The parent strain S288C was studied as a control. The lipid composition (fatty acids, neutral lipids, and phospholipids), respiratory activity (O2 consumption), and ultrastructure were compared in mut...

A survey to determine the trans fatty acid content of a range of processed foods was carried out in response to recent reformulation work by the food industry to lower the artificial trans fatty acid content of processed products. Sixty two composite samples, made up of between 5 and 12 sub-samples, were collected in 2010 and were analysed for fatty acids, and a range of nutrients. The foods an...

INTRODUCTION The studies suggest that trans fatty acids are the most harmful type of fatty acids, and their ingestion leads to an increase in oxidative stress, changes in the plasma levels of LDL cholesterol, and a reduction in n-6 and n-3 fatty acids utilization. The objective of this study was to determine the concentration profiles of elaidic and vaccenic acids in maternal blood plasma in th...

Recent data regarding Trans Fatty Acids (TFAs) have implicated this lipid as being particularly deleterious to human health. TFAs are unsaturated fatty acids that contain at least one non conjugated double bond in the trans configuration, resulting in a more linear shape. The presence of a trans double bond in a fatty acid chain results in a smaller bond angle, or kink, than in a cis double bon...

BACKGROUND The long-term relations between specific types of dietary fat and risk of type 2 diabetes remain unclear. OBJECTIVE Our objective was to examine the relations between dietary fat intakes and the risk of type 2 diabetes. DESIGN We prospectively followed 84204 women aged 34-59 y with no diabetes, cardiovascular disease, or cancer in 1980. Detailed dietary information was assessed a...

The physical properties of common unsaturated fatty acids are altered when they are converted to their geometric isomers. For example, isomerization of the naturally occurring cis acid, oleic acid, to its trans form, elaidic acid, raises its melting point by 30”, changing it from a liquid to a solid at body temperature. Theoretically, such isomeric pairs might be expect.ed to differ in their me...

Although the disadvantages of trans fatty acids (TFAs) are widely mentioned, limited data are available on the TFAs contents of Iranian foods, including fast foods. The aim of this study was to quantify the amounts of common fatty acids in several fast foods in Iran, with specific focus on TFAs. The most commonly consumed fast foods in Iran: sausage, calbas, hamburgers and pizzas, were randomly...

Simple methods are described for the preparation of //-<ms-[l-14C]monounsaturated fatty acids and c is-[l-14C]monounsaturated fatty acids, each with a fairly uniform distribution o f positional isomers, which can serve as mixed substrates in biochemical studies. Methyl trans[ l 14C]octadecenoates and methyl ir<m.s-[l-14C]eicosenoates are prepared by partial catalytic hydrogenation of methyl [1-...