Submit Manuscript | http://medcraveonline.com Abbreviations: TERM: Tissue Engineering and Regenerative Medicine; GAG: Glycosaminoglycans; CEA: Cultured Epithelial Autograft; SCS: Stem Cells; MSCS: Mesenchymal Stem Cells, BMMSCS: Bone Marrow-Derived Mesenchymal Stem Cells; ADSCS: Adipose -Derived Mesenchymal Stem Cells; ECM: Extracellular Matrix; VEFG: Vascular Endothelial Growth Factor; PDGF: P...

Background: Several cells of immune system such as regulatory T cells and macrophages secrete transforming growth factor-β (TGF-β) in response to different stimuli. This cytokine has inhibitory effect on immune system and diminished production of this cytokine is associated with autoimmune disorders. Objective: The aim of this study was to evaluate the influence of opium addiction on serum leve...

Young (4 month) and aged (15-18 months) mice were given intranasal saline or γ--herpesvirus-68 infection. After 21 days, aged, but not young mice, showed significant increases in collagen content and fibrosis. There were no differences in viral clearance or inflammatory cells (including fibrocytes) between infected aged and young mice. Enzyme-linked immunosorbent assays showed increased transfo...

OBJECTIVE During the neonatal and infancy periods, some chronic liver diseases may lead to progressive hepatic fibrosis, which is a condition that can ultimately result in the loss of organ function and severe portal hypertension necessitating hepatic transplantation. In a previous report, pharmacological interventions were demonstrated to modulate hepatic fibrosis induced by bile duct ligation...

AIMS/INTRODUCTION To investigate the effects of vitamin D and its receptor on cytokines expression and podocytes apoptosis. MATERIALS AND METHODS Cultured mouse podocytes were pre-incubated with vitamin D or transiently transfected with small interfering ribonucleic acid (RNA) to knock down the vitamin D receptor. Lipopolysaccharide was used to mimic the inflammation status of diabetes. RES...