Trichinella spiralis nudix hydrolase (TsNd) gene encoding a 46 kDa protein was expressed in Escherichia coli and the potential of recombinant TsNd protein (rTsNd) as an antigen for the serodiagnosis of trichinellosis was investigated by ELISA and compared with those of ELISA with T. spiralis muscle larval excretory–secretory (ES) antigens. The sensitivity of both ELISA was 100% (30/30), for the...

All studies on trichinellosis have been based on the assumption that there is only one cosmopolitan agent of human and animal trichinellosis; Trichinella spiralis (Owen, 1835). In the past, swine and only a few synanthropic animals were considered reservoirs, and the presence of the parasite in sylvatic animals was considered rare. Breeding experiments before, and then biochemical approaches (i...

Epidemiological data on food-borne parasitic zoonoses of Mediterranean and African regions are fragmentary. Several studies indicate that toxoplasmosis frequently occurs in Africa, but the epidemiological patterns in these countries are far from being complete. Serological investigations have been carried out with different methods and the results are not always comparable. Food habits, presenc...

A follow-up study of the class antibody responses to newborn larva (NBL) antigens in individuals involved in an outbreak of human trichinellosis was carried out by ELISA assays. The data showed that similar kinetics of antibody responses of different magnitude developed in trichinellosis patients; it was low by week 3, a peak raised by week 5 and decreased from week 7 up to the end of the study...

The re-emergence of the zoonotic importance of trichinellosis reminds us that this parasite's unique biological features serve it well in helping it to persist in the face of 150 years of efforts to eliminate it from the food chain. Because of Trichinella's re-emergence as an important public health risk, and the consequent stimulation of research, our knowledge of the parasite has grown, espec...

Trichinellosis, is normally not included among those regarded as emerging zoonoses because it has been a public health threat for more than 150 years. However, its dramatic re-emergence in many areas around the world over the past 10±20 years, inspite of a century of veterinary public health efforts to control and eradicate it, justi®es it being included in this group. The reasons for this re-e...

Three cases of human trichinellosis due to Trichinella britovi were reported in 2015 in the Southeast of France resulting from consumption of raw pork sausages (figatelli) prepared in Corsica. Fourteen other people ate figatelli from the same batch but were not infected due to the figatelli being well cooked. This is the first reported human trichinellosis outbreak due to consumption of Corsica...

Due to its role in human Trichinellosis, there are increasing global requirements for reliable diagnostic method for Trichinella spiralis infection in pigs. Consequently, there is a need for selection of potent diagnostic antigen that could be successfully utilized in the diagnosis. Currently, two antigens (somatic and excretory-secretory antigens of T. spiralis larvae) were evaluated for the d...

To assess the global incidence and clinical effects of human trichinellosis, we analyzed outbreak report data for 1986-2009. Searches of 6 international databases yielded 494 reports. After applying strict criteria for relevance and reliability, we selected 261 reports for data extraction. From 1986 through 2009, there were 65,818 cases and 42 deaths reported from 41 countries. The World Health...