BACKGROUND The high degree of phenotypic similarity among Trichophyton species makes their identification difficult. OBJECTIVES The current study aims to establish the use of rolling circle amplification (RCA) based on internal transcribed spacer ribosomal DNA (ITS rDNA) as a powerful, simple, and rapid procedure for distinguishing closely related organisms, and specifically to identify Trich...

Dermatophytosis and superficial mycosis are a major global public health problem that affects 20-25% of the world's population. The increase in fungal resistance to the commercially available antifungal agents, in conjunction with the limited spectrum of action of such drugs, emphasises the need to develop new antifungal agents. Natural products are attractive prototypes for antifungal agents d...

Background and Purpose The epidemiological features of dermatophytoses have been characterized in many geographical locations of Iran, but not in Guilan, North of Iran. This study was carried out to determine the distribution pattern of dermatophytoses and their relevant agents in Guilan, North of Iran, over a period of one year, from April 2010 to April 2011. Materials and Methods The clinic...

the effect of a new anthelmintic compound, leavo-tetramisole, in the mass-treatment of several intestinal helminthes has been evaluated during a study undertaken among the population of the village of zavieh hajian, located about 10 km northwest of dezful, khuzestan.in the autumn of 1972, a total of 83 inhabitants, 65 of whom were simultaneously infected with ascaris, hookworm (ancylostoma) and...

The purpose of this study is to determine the prevalence of tinea pedis and onychomycosis in children of elementary school age and to examine the socio-demographic attributes that may be effective in correlation of both mycoses. 3,390 female and 3,768 male children between ages 6-14 have been examined in seven schools. Skin scrapings and nail samples were taken from 13 students who were suspect...

Introduction: Fungus parasitizing structures rich in keratin, like hair, skin and nails, lead to a dermal inflammatory response with intense itching and cosmetic disfigurement. Hence, diagnosis, treatment and regional epidemiological characteristics of the fungus by in vitro culture are required. Aim and objective: To see the Clinico-mycological pattern of skin and hair infections in dermatolog...

Since traditional diagnosis of dermatophyte infections is slow, we present a rapid new PCR test for detection of Trichophyton spp., Microsporum canis and M. audouinii infections. The performance of the test was evaluated with: 58 dermatophyte isolates; 10 yeast, mould and human DNA control samples; 25 routine specimens from patients suspected of having dermatophytosis; 10 hair specimens from gu...

Five lignans (secoisolariciresinol, pinoresinol, eudesmin, lariciresinol, and lariciresinol-4-methyl ether) were isolated from an MeOH extract from Araucaria araucana (Mol.) K. Koch wood for the first time in this species and their structures determined with spectroscopic methods. The antimicrobial activities of these compounds were determined for the bacteria Citrobacter sp., Bacillus subtilis...

BACKGROUND Neospora caninum, an obligate intracellular protozoan parasite, is recognized as a major cause of abortion in cattle, while limited information is presently available on the seroprevalence of Neospora antibodies in horses' worldwide. The aim of the present study was to determine serologic prevalence of Neospora infection in horses in Iran. METHODS Sera from 150 horses from Mashhad ...