Mivacurium chloride (BW B1090U) is a new, short-acting non-depolarizing neuromuscular blocking agent. It is a synthetic bis-benzylisoquinolinium diester, which is hydrolysed rapidly by plasma cholinesterase. This study compares mivacurium, atracurium and vecuronium by continuous i.v. infusion. The duration of mivacurium infusion ranged from 29.5 to 286 min. The steady state infusion rates neces...

Sphere-like shaped cobalt oxide nanoparticles (Co3O4) were synthesized by a simple wet chemical method using cobalt chloride as precursor and cetyl trimethylammonium bromide (CTAB) as surfactant. Their structural and surface morphologial properties were characterized by high resolution transmission electron microscopy (HRTEM), field emission scanning electron microscopy (FESEM) and X-ray diffra...

A Triton X-100 extract of electric tissue was subjected to a single step affinity chromatography using either of two affinity gels: [N-(6-aminocaproyl)-p-aminobenzyl]trimethylammonium bromide or methyl[(6-aminocaproyl-6'-aminocaproyl)-3-amino]pyridinium bromide attached to Sepharose 4B. Specific elution of the acetylcholine receptor-I (AcChR-I) with low concentration of a bis-quaternary agonist...

Whilst there is a large body of evidence looking at the design of cationic liposomes as transfection agents, correlates of formulation to function remain elusive. In this research, we investigate if lipid packaging can give further insights into transfection efficacy. DNA lipoplexes composed of 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) or 1,2-distearoyl-sn-glycero-3-phosphoethanolami...

The nonlinear flow behavior of a viscoelastic gel formed due to entangled, cylindrical micelles in aqueous solutions of the surfactant cetyl trimethylammonium tosilate (CTAT) has been studied. On subjecting the system to a step shear rate lying above a certain value, the shear and normal stresses show interesting time dependent behavior. The analysis of the measured time series shows the existe...

Molecularly imprinted polymers are synthetic materials designed to selectively bind to a templated molecule. In this study, the effect of including both positive and negative charges simultaneously into the hydrogel network on the selective recognition properties of the MIP is examined. Using 3-methacrylamidopropyl trimethylammonium chloride (MAPTAC) as a cationic monomer and 2-acrylamido-2meth...